Endocrine Pharmacology — Flashcards

One mechanism by which metformin decreases gluconeogenesis is via _____ of the enzyme AMP-activated protein kinase (AMPK)

_____ is a drug that inhibits glucocorticoid biosynthesis via inhibition of the enzyme cholesterol desmolase

The azole _____ inhibits the adrenal enzyme 17,20-desmolase

_____ inhibitors, such as finasteride may be used to treat benign prostatic hyperplasia because they block activation of testosterone (to DHT) in the prostate

Exogenous testosterone causes _____ LDL and decreased HDL

_____ is an anti-progestin used to terminate pregnancy when combined with misoprostol (PGE1 analog)

Thyroid, Pituitary, & Adrenal _____ are a class of drugs that are useful in the treatment and prevention of postmenopausal osteoporosis

_____ is more selective to type 2 enzyme whereas dutasteride inhibits both type 1 and type 2 5-alpha reductase

Absolute contraindications to combined oral contraceptive use: Known or suspected carcinoma of the _____, female reproductive tract

First Aid Pharmacology: Endocrine _____ is a synthetic analog of aldosterone with little glucocorticoid effects