Neuroblastoma — Flashcards

The most common extra-cranial solid neoplasm in children is _____

Good prognosis in neuroblastoma is associated with _____diploidy.

Mutations in MYCN can cause _____ due to a resultant amplification of the transcription factor's activity (nuclear regulator)

Chromosome 1p and 11q losses are associated with a _____ prognosis in neuroblastoma

The most common intra-abdominal neoplasm in children is _____

Neuroblastoma is characterized by increased levels of _____ and vanillylmandelic acid (VMA) in the urine (catecholamine metabolites)

The most common presentation for a _____ is abdominal distention with a firm, irregular mass that can cross the midline

Wilms tumor presents as a large, _____ flank mass (most common presentation) and/or hematuria.

Most unilateral Wilms tumors are treated by _____ followed by nephrectomy.

Age younger than _____ year or presentation in adolescence or adulthood is a bad prognostic marker for ALL