Renal Tubular Disorders — Flashcards

Flashcard 1: Which morphological abnormalities can lead to the development of nephrogenic diabetes insipidus?_____

Answer: ureteral obstruction

Flashcard 2: _____ syndrome, also called as non-neurogenic neurogenic bladder, is a disorder involving failure of the external sphincter to relax during voiding

Answer: Hinman

Flashcard 3: AR steroid resistant focal segmental glomerulosclerosis (non-Finnish) can be caused by mutation in _____ gene.

Answer: NPHS 2 (podocin)

Flashcard 4: _____ syndrome presents with _____-onset nephrotic syndrome, progressive renal insufficiency, _____ genitalia, and Wilms tumor.

Answer: Denys-Drash; early; ambiguous

Flashcard 5: Recurrent hematuria with eumorphic RBCs may be seen in which renal channelopathy?

Answer: Bartter syndrome

Extra: Bartter syndrome is a renal tubulopathy (channelopathy) that presents with hypercalciuria. This can lead to nephrocalcinosis and nephrolithiasis, which may manifest as recurrent hematuria with eumorphic (non-glomerular) RBCs.

Flashcard 6: Urinary incontinence _____ times / week for ≥ 3 months in persons ≥ 5 years old is known as Enuresis

Answer: ≥ 2

Flashcard 7: Wilms tumor may present with _____ due to increased renin secretion

Answer: hypertension

Flashcard 8: Newborns males with posterior urethral valves may have a _____ mass and bilateral hydronephrosis

Answer: midline

Flashcard 9: There is an increased risk for _____ rickets with proximal renal tubular acidosis due to Fanconi Syndrome

Answer: hypophosphatemic

Flashcard 10: The _____ form of polycystic kidney disease typically presents in infants

Answer: autosomal recessive