Hypertension in Children — Flashcards

Flashcard 1: AR congenital nephrotic syndrome (Finnish type) is caused by a mutation in the _____ gene

Answer: nephrin (NPHS1)

Flashcard 2: A 6 yr old child presents with malignant hypertension. The Drug of choice is -

Answer: Sodium Nitroprusside

Flashcard 3: AR steroid resistant focal segmental glomerulosclerosis (non-Finnish) can be caused by mutation in _____ gene.

Answer: NPHS 2 (podocin)

Flashcard 4: Wilms tumor may present with _____ due to increased renin secretion

Answer: hypertension

Flashcard 5: Chronic _____ disease is an FDA approved indication for growth hormone (GH) therapy.

Answer: kidney

Flashcard 6: Target urine output to prevent potential over-resuscitation in a child (1 year to puberty)

Answer: 1 mL/kg/hr

Extra: Urine output targets in pediatric resuscitation: - Infants (<1 year): 2 mL/kg/hr - Children (1 year to puberty): 1 mL/kg/hr - Adolescents (>puberty): 0.5 mL/kg/hr Maintaining these targets helps ensure adequate end-organ perfusion while minimizing the risk of fluid overload (over-resuscitation).

Flashcard 7: Urinary incontinence _____ times / week for ≥ 3 months in persons ≥ 5 years old is known as Enuresis

Answer: ≥ 2

Flashcard 8: Newborns males with posterior urethral valves may have a _____ mass and bilateral hydronephrosis

Answer: midline

Flashcard 9: There is an increased risk for _____ rickets with proximal renal tubular acidosis due to Fanconi Syndrome

Answer: hypophosphatemic