Development of Immune System — Flashcards

Flashcard 1: Delayed separation of umbilical cord, after 1 month is associated with _____ (LAD) syndromes.

Answer: leukocyte adhesion deficiency

Flashcard 2: The symptoms of Wiskott-Aldrich syndrome may be remembered with the mnemonic "WATER": W: Wiskott A: Aldrich T: _____ E: Eczema R: Recurrent (pyogenic) infections

Answer: Thrombocytopenia (fewer and smaller platelets)

Flashcard 3: Varicella and MMR vaccines can be given in HIV-infected children if the CD4 percentage is _____%

Answer: > 15%

Extra: Live vaccines are generally contraindicated in severely immunocompromised patients. In HIV-infected children, MMR and Varicella can be administered if the CD4 percentage is > 15%. **OPV is strictly contraindicated** in all immunocompromised individuals and their household contacts due to the risk of vaccine-associated paralytic polio (VAPP).

Flashcard 4: The measles vaccine is administered after a gap of _____ following the administration of Immunoglobulin (Ig).

Answer: 3 months

Extra: • If Ig is given first: Wait at least 3 months (up to 11 months depending on the dose) before giving the measles vaccine. • If the vaccine is given first: Wait at least 2 weeks before giving Ig.

Flashcard 5: _____-positive oligoarthritis is a subtype of JIA associated with the highest risk for uveitis.

Answer: ANA

Flashcard 6: Uveitis in juvenile idiopathic arthritis is usually _____terior, non-granulomatous and bilateral.

Answer: an

Flashcard 7: The symptoms of Job syndrome may be remembered with the mnemonic _____: F: coarse Facies A: cold (noninflamed) staphylococcal Abscesses T: retained primary Teeth E: increased IgE D: Dermatologic problems (eczema)

Answer: FATED

Flashcard 8: _____-positive oligoarticular juvenile Idiopathic arthritis (JIA) is associated with the highest risk for iridicyclitis (uveitis).

Answer: ANA

Flashcard 9: What is the treatment for Henoch-Schonlein purpura?_____

Answer: Disease is self-limited