White Blood Cell Disorders — Flashcards

Flashcard 1: Patients with beta-thalassemia major are at risk of _____ with parvovirus B19 infection of erythroid precursors

Answer: aplastic crisis

Flashcard 2: The curative treatment for Chediak Higashi syndrome is _____

Answer: bone marrow transplantation

Flashcard 3: Anaemia in a 12-14 year old child is defined as a hemoglobin level of less than:

Answer: 12 g/dL

Extra: WHO Hemoglobin thresholds for diagnosis of anemia: - Children (6–59 months): < 11 g/dL - Children (5–11 years): < 11.5 g/dL - Children (12–14 years): < 12 g/dL - Non-pregnant women (15+ years): < 12 g/dL - Men (15+ years): < 13 g/dL

Flashcard 4: Patients with Down syndrome, who develop transient myeloproliferative disorder require close follow-up, because 20 30% will develop _____ leukemia by 3 years of life

Answer: acute megakaryocytic

Flashcard 5: _____ leukemia is associated with Down syndrome; usually arises before the age of 5

Answer: Acute megakaryoblastic

Flashcard 6: On complete blood count, patients with Systemic Juvenile Idiopathic Arthritis will frequently present with: - _____ RBCs - increased WBCs - increased Platelets

Answer: decreased

Flashcard 7: Beta-thalassemia _____ is characterized by expansion of hematopoiesis into facial bones, leading to "chipmunk facies"

Answer: major

Flashcard 8: _____ syndrome is a syndrome of thrombocytopenia and consumptive coagulopathy in a patient of hemangioma

Answer: Kasabach-Merritt

Flashcard 9: _____ is a common presenting sign of sickle cell anemia in infants (age group)

Answer: Dactylitis

Flashcard 10: Kids with sickle cell disease should undergo _____ starting at age of 2 yrs to reduce the incidence of overt stroke

Answer: transcranial doppler ultrasound