Evaluation of Bleeding Tendencies — Flashcards

Flashcard 1: Hb _____ levels are increased in juvenile chronic myeloid leukemia (JMML)

Answer: F

Flashcard 2: Which objective audiometry test is considered unsuitable for testing hearing in infants and young children because it is affected by sleep and sedation?

Answer: CERA (Cortical Evoked Response Audiometry)

Extra: CERA is a late latency response (LLR) that is highly dependent on the patient's state of alertness and is significantly affected or abolished by sleep and sedation. Since infants and uncooperative children often need to be asleep or sedated for objective testing, CERA is considered unsuitable for them. In contrast, BERA (Brainstem Evoked Response Audiometry) is a short-latency response that is not affected by sleep or sedation, making it the gold standard for objective hearing assessment in children.

Flashcard 3: _____ syndrome is the most common cause of megaloblastic anemia due to cobalamin deficiency in infancy in Western countries

Answer: Imerslund-Grasbeck

Flashcard 4: Transient myeloproliferative disease, usually resolves spontaneously in the 1st _____ months of life

Answer: 3

Flashcard 5: Anaemia in a 2-5 year old child is defined as a hemoglobin level of

Answer: < 11 g/dL

Flashcard 6: _____ is a common presenting sign of sickle cell anemia in infants (age group)

Answer: Dactylitis

Flashcard 7: Beta-thalassemia _____ is characterized by expansion of hematopoiesis into facial bones, leading to "chipmunk facies"

Answer: major

Flashcard 8: Anaemia in a 12-14 year old child is defined as a hemoglobin level of less than:

Answer: 12 g/dL

Extra: WHO Hemoglobin thresholds for diagnosis of anemia: - Children (6–59 months): < 11 g/dL - Children (5–11 years): < 11.5 g/dL - Children (12–14 years): < 12 g/dL - Non-pregnant women (15+ years): < 12 g/dL - Men (15+ years): < 13 g/dL

Flashcard 9: Patients with Down syndrome, who develop transient myeloproliferative disorder require close follow-up, because 20 30% will develop _____ leukemia by 3 years of life

Answer: acute megakaryocytic