Restrictive Pulmonary Diseases — Flashcards

Flashcard 1: Which subtypes of idiopathic interstitial pneumonia are associated with smoking?_____

Answer: Respiratory bronchiolitis associated ILD (RB-ILD) and Desquamative interstitial pneumonia (DIP)

Flashcard 2: Most pneumoconiosis involves the _____ lobes of the lung (coal worker's pneumoconiosis (CWP), silicosis, berylliosis), except asbestosis

Answer: upper

Flashcard 3: What is the classic manifestation of **chronic** lung transplant rejection, characterized by inflammation and fibrosis of the small airways (bronchioles)?

Answer: Bronchiolitis obliterans

Extra: In contrast, **acute** lung transplant rejection (weeks to months) is characterized by perivascular and interstitial lymphocytic infiltrates.

Flashcard 4: _____ is likely related to cyclical lung injury, with TGF-β from injured pneumocytes inducing increased collagen deposition and fibrosis

Answer: Idiopathic pulmonary fibrosis

Flashcard 5: _____ emphysema may develop in simple coal worker's pneumoconiosis

Answer: Centriacinar/Centrilobular

Flashcard 6: _____ is an immunologically mediated reaction that generates granulomas in response to inhaled organic antigens (e.g. pigeon breeders lung)

Answer: Hypersensitivity pneumonitis

Flashcard 7: Histopathology showing the _____ effect are suggestive of a small cell carcinoma of the lung.

Answer: Azzopardi

Flashcard 8: _____ bodies are seen in cryptogenic organizing pneumonia.

Answer: Masson

Flashcard 9: The diagnosis is _____ carcinoma of the lung.

Answer: large cell

Flashcard 10: Asbestos bodies contain _____ and thus may be visualized using a Prussian blue stain

Answer: iron