Ovarian Diseases and Tumors — Flashcards

Flashcard 1: _____ cell nests are seen in Brenner tumor of the ovary

Answer: Walthard

Flashcard 2: One type of a rare ovarian surface epithelial tumor is a _____ tumor, which is composed of bladder-like epithelium (urothelium)

Answer: Brenner

Flashcard 3: A _____ is an ovarian germ cell tumor composed of large primitive "oocyte-like" cells with clear cytoplasm and central nuclei; described as "fried egg" cells

Answer: dysgerminoma

Flashcard 4: Testicular tumors may arise from either _____ or sex-cord stroma

Answer: germ cells

Flashcard 5: _____ cystadenoma is a benign tumor lined with fallopian tube-like epithelium; often bilateral

Answer: Serous

Flashcard 6: Embryonal carcinoma may have increased levels of _____ and normal or elevated levels of AFP

Answer: hCG

Flashcard 7: Grade _____ endometrial carcinoma: characterized by predominantly solid growth (> 50%) and loss of glandular architecture.

Answer: 3

Extra: FIGO Grading for Endometrioid Adenocarcinoma: - Grade 1: ≤ 5% solid growth (well-differentiated) - Grade 2: 6–50% solid growth (moderately differentiated) - Grade 3: > 50% solid growth (poorly differentiated) Note: Solid growth is defined as non-squamous and non-morular growth. "Back-to-back" glands with minimal stroma is a feature of Grade 1/well-differentiated carcinoma, whereas Grade 3 is defined by the loss of glandular architecture and presence of solid sheets.

Flashcard 8: The following image represents the _____ carcinoma subtype of invasive ductal carcinoma:

Answer: tubular

Flashcard 9: The H&E stained specimen shows endometrial glands and surrounding stroma in myometrium, suggestive of _____

Answer: Adenomyosis

Flashcard 10: In regards to cervical epithelium, if the tissue sample on the left is normal, is the tissue sample on the right: mildly dysplastic, moderately dysplastic, or severely dysplastic / carcinoma in situ? _____ VS

Answer: Severely Dysplastic / Carcinoma in Situ