Pancreatic Pathology Indian Medical PG Flashcards - Medical Study Cards
Master Pancreatic Pathology with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Pancreatic Pathology Flashcard Deck - 35 Cards
Flashcard 1: Type _____ diabetes mellitus is associated with deposition of amylin (islet amyloid polypeptide) in the islets of the pancreas
Answer: II
Flashcard 2: Mucinous cystadenomas are most commonly found in the _____ and tail of the pancreas
Answer: body
Flashcard 3: Pancreatic adenocarcinoma is CK 7 _____ and CK 20 negative
Answer: positive
Flashcard 4: Cyst fluid analysis in _____ will show a high CEA level and low level of cyst fluid amylase
Answer: MCNs
Flashcard 5: Pancreatic adenocarcinomas are solid, _____ tumors, characterized by neoplastic tubular glands within a markedly desmoplastic fibrous stroma
Answer: scirrhous
Flashcard 6: MCNs of the pancreas contain _____-producing tall columnar epithelium
Answer: mucin
Flashcard 7: Carcinomas situated in the _____ of the pancreas are usually larger than the head
Answer: body
Flashcard 8: _____ is due to autodigestion of pancreatic parenchyma by pancreatic enzymes
Answer: Acute pancreatitis
Flashcard 9: _____ cystadenoma of the pancreas contains mucin-producing epithelium with ovarian-like stroma on histology
Answer: Mucinous
Flashcard 10: _____ invasion is characteristic of pancreatic ductal adenocarcinoma
Answer: Perineural
Flashcard 11: Hereditary pancreatitis may be caused by mutations in the gene _____ encoding for the cleavage site of trypsinogen or the SPINK1 protein
Answer: PRSS1
Flashcard 12: _____ cystadenoma of the pancreas presents most commonly in peri-menopausal females
Answer: Mucinous
Flashcard 13: _____ insufficiency precedes endocrine insufficiency in chronic pancreatitis (endocrine/exocrine)
Answer: Exocrine
Flashcard 14: What is the risk of malignancy in serous cystadenomas of pancreas?_____
Answer: low
Flashcard 15: _____ cystadenoma of the pancreas stains positive for estrogen and progesterone in most cases
Answer: Mucinous
Flashcard 16: Acute _____ is seen in hypothermia.
Answer: pancreatitis (GI pathology)
Flashcard 17: _____ stone is the most common type of stone formed in chronic pancreatitis.
Answer: Calcium carbonate
Flashcard 18: What is the most frequently altered tumor supressor in pancreatic carcinoma?_____
Answer: CDKN2A on chromosome 9p
Flashcard 19: What is the risk of malignancy in mucinous cystadenomas of pancreas?_____
Answer: high
Flashcard 20: _____ cystadenoma is the most common type of cystic neoplasms of the pancreas
Answer: Mucinous
Flashcard 21: What cystic neoplasm of the pancreas presents with solitary cyst, with fine septations and surrounded by a rim of eggshell calcification?_____
Answer: Mucinous cystadenoma
Flashcard 22: Which cystic neoplasm of the pancreas presents with uniform distribution across the pancreas?_____
Answer: Serous cystadenoma
Flashcard 23: Most common site of thrombosis in chronic pancreatitis is the _____ vein
Answer: splenic
Flashcard 24: What are the infiltrating cells in Type 1 autoimmune pancreatitis?_____
Answer: IgG4+plasma cells
Flashcard 25: Earliest genetic change in carcinoma pancreas is _____ mutation
Answer: KRAS
Flashcard 26: _____ appearance is seen due to presence of microcysts in serous cystadenoma of pancreas
Answer: Honeycomb
Flashcard 27: The most common neuroendocrine tumor of the pancreas is an _____.
Answer: insulinoma
Flashcard 28: What hormone receptors are positive in mucinous cystadenomas of the pancreas?_____
Answer: estrogen and progesterone
Flashcard 29: _____ cystadenoma of pancreas presents with glycogen rich cells on histology
Answer: Serous
Flashcard 30: _____ are the most common cystic neoplasms of the pancreas.
Answer: Mucinous cystadenomas (MCNs)
Flashcard 31: _____ cystadenoma of pancreas presents with honeycomb appearance on gross examination due to microcysts
Answer: Serous
Flashcard 32: Which cystic neoplasm of the pancreas has low levels of CEA and amylase?_____
Answer: Serous cystadenoma
Flashcard 33: Microscopic examination of serous cystadenomas of pancreas reveals multiloculated, _____-rich small cysts.
Answer: glycogen
Flashcard 34: What is the demographic of mucinous cystadenomas of the pancreas?_____
Answer: Perimenopausal females
Flashcard 35: What is the most frequently altered oncogene in pancreatic carcinoma?_____
Answer: K-RAS on chromosome 12p
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