_____ is the most commonly mutated gene in sporadic breast carcinomas
#2
The size of M-BCR ABL (Major BCR) protein in t(9;22) associated with chronic myeloid leukemia (CML) is _____ kDa.
#3
Alagille syndrome is associated with mutations in _____ gene in 10% of patients
#4
Activating mutation in _____ is responsible for bladder carcinoma.
#5
_____ is a molecular test in breast cancer that is a 21-gene assay
#6
Best's disease is caused by a mutation on a _____ gene.
#7
In Array based Comparative Genomic Hybridization, if the test sample has amplification, then some spots on the array will flouresce _____.
#8
Gain-of-function mutations in _____ gene has been linked with Pityriasis Rubra Pilaris (PRP)
#9
Mutations that cause _____ of the HER2 receptor can precipitate development of certain Breast* and Gastric* Cancers by amplifying the signal transduction
#10
_____ disease is due to a deletion of the VHL gene on chromosome 3p, leading unregulated activity of HIF1a
Pharmacogenomics Indian Medical PG Flashcards - Medical Study Cards
Master Pharmacogenomics with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Pharmacogenomics Flashcard Deck - 10 Cards
Flashcard 1: _____ is the most commonly mutated gene in sporadic breast carcinomas
Answer: TP53
Flashcard 2: The size of M-BCR ABL (Major BCR) protein in t(9;22) associated with chronic myeloid leukemia (CML) is _____ kDa.
Answer: 210
Flashcard 3: Alagille syndrome is associated with mutations in _____ gene in 10% of patients
Answer: NOTCH2
Flashcard 4: Activating mutation in _____ is responsible for bladder carcinoma.
Answer: HRAS
Flashcard 5: _____ is a molecular test in breast cancer that is a 21-gene assay
Answer: Oncotype Dx
Flashcard 6: Best's disease is caused by a mutation on a _____ gene.
Answer: bestophin (VMD2)
Flashcard 7: In Array based Comparative Genomic Hybridization, if the test sample has amplification, then some spots on the array will flouresce _____.
Answer: red
Flashcard 8: Gain-of-function mutations in _____ gene has been linked with Pityriasis Rubra Pilaris (PRP)
Answer: CARD14
Flashcard 9: Mutations that cause _____ of the HER2 receptor can precipitate development of certain Breast* and Gastric* Cancers by amplifying the signal transduction
Answer: overexpression
Flashcard 10: _____ disease is due to a deletion of the VHL gene on chromosome 3p, leading unregulated activity of HIF1a
Answer: Von Hippel-Lindau
Keywords: Pharmacogenomics flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
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