Anti-infective Agents — Flashcards

Flashcard 1: _____ and amphotericin-B are antifungals that can be given intravitreally.

Answer: Voriconazole

Flashcard 2: _____ eyedrops is the drug of choice for uncomplicated filamentous fungal keratitis, without intraocular or anterior chamber extension

Answer: Natamycin

Flashcard 3: Which drugs are used for mycotic ulcers with hypopyon or perforation or suspected endophthalmitis (intraorbital extension)?_____

Answer: Ketoconazole/Voriconazole

Flashcard 4: What drugs are used for the mainstay of treatment for uveitis?_____

Answer: Steroids and cycloplegics

Flashcard 5: Which antimalarials are associated with bull's eye maculopathy?_____

Answer: Chloroquine and hydroxychloroquine

Flashcard 6: In neonates with conjunctivitis, _____ (late onset) is treated with oral Erythromycin, while Neisseria gonorrhoeae (early onset) is treated with Ceftriaxone.

Answer: Chlamydia trachomatis

Extra: Neonatal conjunctivitis (Ophthalmia neonatorum) timing and treatment: • Chemical (<24h): Due to silver nitrate; resolves spontaneously. • Neisseria gonorrhoeae (2–5 days): Most severe; treat with systemic Ceftriaxone. • Chlamydia trachomatis (5–14 days): Most common; treat with oral Erythromycin. Note: Oral erythromycin in neonates is associated with an increased risk of infantile hypertrophic pyloric stenosis. Topical erythromycin is used for prophylaxis, not treatment.

Flashcard 7: Drug of choice for herpes simplex keratitis is :

Answer: Acyclovir

Flashcard 8: Triple therapy for ocular toxoplasmosis: Systemic _____, Pyrimethamine and Sulfadiazine

Answer: steroids

Flashcard 9: _____ implant is a dexamethasone intravitreal implant used to treat secondary macular edema

Answer: Ozurdex

Flashcard 10: Latanoprost and bimatoprost can produce _____ pigmentation in the iris and can cause eyelash growth

Answer: brown