Lens Anatomy and Physiology — Flashcards

Flashcard 1: What is the most important antioxidant mechanism in the lens?_____

Answer: Reduced glutathione

Flashcard 2: Y-shaped sutures are characteristic of the _____ nucleus of the lens.

Answer: fetal

Extra: In the fetal nucleus, the anterior suture is an upright 'Y' and the posterior suture is an inverted 'Y'. The embryonic nucleus has no sutures, while the infantile and adult nuclei have more complex star-shaped (dendritic) sutures.

Flashcard 3: Majority of the energy requirement in the lens is met by _____

Answer: glycolysis

Flashcard 4: _____ nucleus of the lens is formed from birth to puberty

Answer: Infantile

Flashcard 5: The lens capsule is the thinnest at the _____ and thickest, at the pre-equator region.

Answer: posterior pole

Flashcard 6: Subluxation or dislocation of the lens may occur due to degeneration of _____ in the hypermature stage of cataract.

Answer: zonules

Flashcard 7: The crystalline lens derives its nutrition from the _____.

Answer: aqueous humor

Flashcard 8: _____ 26 (MIP 26)/Aquaporin 0 in the lens is responsible for maintaining transparency by transporting water and glycerol across the lens.

Answer: Major intrinsic protein

Flashcard 9: Increased accumulation of sorbitol in the lens in diabetes leads to secondary _____

Answer: Osmotic overhydration (not cataract)

Flashcard 10: Wilson's disease and penetrating trauma is associated with _____ cataract

Answer: sunflower