Diseases of the Cornea — Flashcards

Flashcard 111: _____ is used for the intermediate-term preservation of cornea, up to 7-14 days

Answer: Chondroitin sulfate-based media (e.g., Optisol-GS, Dexsol)

Extra: Corneal preservation methods based on duration: • Short-term (up to 4 days): M-K (McCarey-Kaufman) medium. • Intermediate-term (up to 2 weeks): Chondroitin sulfate-based media (e.g., Optisol-GS, Dexsol). • Long-term (up to 4 weeks): Organ culture (at 31°C to 37°C). • Very long-term: Cryopreservation.

Flashcard 112: _____ KPs are seen in Acute hemorrhagic uveitis

Answer: Red

Flashcard 113: What are the common causes of interstitial keratitis (IK)?

Answer: • Syphilis (most common; congenital) • Tuberculosis (TB) • Leprosy • Sarcoidosis • Viral (Herpes simplex, Zoster, Mumps) • Acanthamoeba (protozoal) • Cogan syndrome • Lyme disease

Extra: Interstitial keratitis (IK) is a non-ulcerative inflammation of the corneal stroma. Clinical features include: - Pain, photophobia, lacrimation. - "Salmon patch" appearance: Circumcorneal deep vascularization in the active stage. - Ghost vessels: Remnants of vessels seen in the healed stage.

Flashcard 114: Bilateral whorl-like corneal pattern of cream coloured lines on cornea is seen in _____

Answer: Vortex Keratopathy

Flashcard 115: What is the most common corneal degeneration?_____

Answer: Arcus senilis

Flashcard 116: In _____, pannus is characterized by progressive infiltration occurring ahead of vascularization.

Answer: Trachoma

Flashcard 117: _____ is used for the long-term preservation of cornea, up to 30 days

Answer: Modified Eagle's medium

Flashcard 118: _____ dystrophy is the least common corneal dystrophy

Answer: Macular

Flashcard 119: Which layer of the cornea is most metabolically active?_____

Answer: Endothelium

Flashcard 120: Progressive atrophy of _____ is a clinical entity of iridocorneal endothelial syndrome (ICE).

Answer: iris stroma