Vaccination in Special Populations — Flashcards

Flashcard 1: Measles vaccine is based on the _____ strain

Answer: Edmonston-Zagreb

Flashcard 2: A _____ is an inactivated bacterial exo-toxin used for vaccination

Answer: toxoid

Flashcard 3: Which part of embryonated egg is used for making vaccine of Vaccinia, Variola, HSV 1 and HSV 2?_____

Answer: Chorioallantoic membrane

Flashcard 4: Bacterial _____ polysaccharides are the basis for many vaccines

Answer: capsular

Flashcard 5: Smallpox vaccine is a _____ vaccine (Vaccinia virus).

Answer: live virus

Extra: The Smallpox vaccine contains live **Vaccinia** virus (not the Variola virus that causes smallpox). It is a heterologous live virus vaccine that provides cross-protection. Current versions include ACAM2000 (replicating) and JYNNEOS (Modified Vaccinia Ankara - MVA, non-replicating).

Flashcard 6: Which part of the embryonated egg is used for the cultivation of Influenza and Mumps viruses?

Answer: Allantoic cavity

Extra: Cultivation of viruses in embryonated eggs: - **Allantoic cavity**: Influenza, Mumps, Newcastle disease virus. - **Amniotic cavity**: Primary isolation of Influenza virus. - **Chorioallantoic membrane (CAM)**: Poxviruses (Variola, Vaccinia), HSV. - **Yolk sac**: Chlamydia, Rickettsia, Rabies (Flury strain). - **Chick embryo**: Yellow fever (17D strain).

Flashcard 7: Recipient VAPP mostly occurs due to mutated _____ strain

Answer: P3

Extra: VAPP: Vaccine-associated paralytic polio. It is most commonly associated with Type 3 (P3) in recipients and Type 2 (P2) in contacts.

Flashcard 8: VNA after rabies vaccine is max. by _____

Answer: 14 days

Flashcard 9: leprosy vaccine uses _____ strain

Answer: MIP(mycobacterium indicus pranii)

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Flashcard 10: _____ type of vaccine is used for Hep B

Answer: recombinant

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