New Vaccine Technologies — Flashcards

Flashcard 1: Which part of embryonated egg is used for making vaccine of Vaccinia, Variola, HSV 1 and HSV 2?_____

Answer: Chorioallantoic membrane

Flashcard 2: Bacterial _____ polysaccharides are the basis for many vaccines

Answer: capsular

Flashcard 3: Smallpox vaccine is a _____ vaccine (Vaccinia virus).

Answer: live virus

Extra: The Smallpox vaccine contains live **Vaccinia** virus (not the Variola virus that causes smallpox). It is a heterologous live virus vaccine that provides cross-protection. Current versions include ACAM2000 (replicating) and JYNNEOS (Modified Vaccinia Ankara - MVA, non-replicating).

Flashcard 4: The HPV vaccines use virus-like particles (VLPs) that consist of the HPV _____ major capsid protein

Answer: L1

Flashcard 5: Recipient VAPP mostly occurs due to mutated _____ strain

Answer: P3

Extra: VAPP: Vaccine-associated paralytic polio. It is most commonly associated with Type 3 (P3) in recipients and Type 2 (P2) in contacts.

Flashcard 6: VNA after rabies vaccine is max. by _____

Answer: 14 days

Flashcard 7: leprosy vaccine uses _____ strain

Answer: MIP(mycobacterium indicus pranii)

Extra: 

Flashcard 8: _____ type of vaccine is used for Hep B

Answer: recombinant

Extra: 

Flashcard 9: A level of _____ antibodies is considered protective after rabies vaccination.

Answer: ≥ 0.5 IU/mL

Flashcard 10: Seroconversion of anti-rabies vaccine is tested by _____

Answer: VNA (Virus Neutralizing Antibody)