Autoinflammatory Syndromes — Flashcards

Flashcard 1: The characteristics of SLE may be remembered with the mnemonic "RASH OR PAIN":R: _____A: Arthritis (usually involving > 2 joints)S: Serositis (pleuritis and pericarditis)H: Hematologic disorders (e.g. cytopenias)O: Oral or nasopharyngeal ulcers (usually painless)R: Renal diseaseP: PhotosensitivityA: Antinuclear antibodiesI: Immunologic disorder (anti-dsDNA, anti-Sm, antiphospholipid) N: Neurologic disorder (seizures, psychosis)

Answer: Rash (malar or discoid)

Flashcard 2: Catastrophic antiphospholipid antibody syndrome (CAPS) is a rapidly progressive thromboembolic disorder simultaneously involving _____ or more organ systems or tissues.

Answer: three

Flashcard 3: _____ syndrome is rheumatoid arthritis with neutropenia and splenomegaly

Answer: Felty

Flashcard 4: Autoantibodies seen in dermatomyositis include anti-_____, anti-NXP2, anti-MDA5, and anti-TIF1-gamma.

Answer: Mi-2

Flashcard 5: Anti-_____ antibodies are associated with dermatomyositis featuring gottron papules and heliotrope rash

Answer: Mi2

Flashcard 6: Methotrexate with _____ is used for management of rheumatoid arthritis with joint destruction and disability.

Answer: anti-TNF

Flashcard 7: _____ scleritis _____ inflammation is seen in long standing cases of rheumatoid arthritis

Answer: Necrotizing

Flashcard 8: This image is an example of a "_____" deformity, which is most commonly associated with Rheumatoid arthritis

Answer: swan neck

Flashcard 9: caplan syndrome includes _____

Answer: rheumatoid arthritis + pneumoconiosis

Extra: 

Flashcard 10: Serum sickness-like reactions are associated with some drugs acting as _____ and infections (ex. HBV)

Answer: haptens (ex. penicillin)