Metastatic Skin Tumors — Flashcards

Flashcard 1: Melanoma may be distinguished from extramammary paget disease of the vulva by the following immunohistological features: 1. PAS _____ 2. Keratin - 3. S100 +

Answer: -

Flashcard 2: Regarding the incidence of the three main types of skin cancer in the United States, _____ > Squamous >> Melanoma

Answer: Basal

Flashcard 3: _____ is a variant of Mycosis Fungoides (CTCL) characterized by boggy plaques with follicular prominence and histological evidence of mucinous degeneration of the hair follicles.

Answer: Folliculotropic Mycosis Fungoides

Extra: This variant of Mycosis Fungoides (CTCL) is histologically characterized by **follicular mucinosis** (accumulation of mucin within the hair follicle epithelium). Clinical features include: - Boggy plaques or tumors - Follicular prominence (alopecia mucinosa) - Pruritus - Often involves the head and neck region.

Flashcard 4: Cutaneous horn can show features of _____ carcinoma at its base

Answer: squamous cell

Flashcard 5: Neuroendocrine carcinoma of the skin arises from _____ cells

Answer: Merkel

Flashcard 6: _____ type is the commonest type of basal cell carcinoma

Answer: Nodular

Flashcard 7: _____ is a clinical-histological pattern (often associated with Cutaneous T-cell Lymphoma) characterized by boggy cutaneous plaques with follicular prominence and accumulation of mucin within the hair follicles.

Answer: Follicular mucinosis

Flashcard 8: Which skin cancer presents as an ulcerative red lesion with frequent scale? _____

Answer: Squamous cell carcinoma

Flashcard 9: Superficial _____ cell carcinoma may present as a scaling plaque

Answer: basal

Flashcard 10: DNA analysis of person with fine scaly erythematous plaques, showing clonal arrangements of T cell receptor genes, is suggestive of _____

Answer: mycosis fungoides