Vitiligo — Flashcards

Flashcard 1: _____ melasma appears slightly grey or bluish on gross examination and shows less color contrast with Wood's lamp.

Answer: Dermal

Extra: Wood's lamp examination (365 nm) helps determine the depth of melanin in melasma: - **Epidermal:** Pigment is intensified (more contrast). - **Dermal:** Pigment does not intensify (less contrast/no change). - **Mixed:** Mixture of both patterns (most common type).

Flashcard 2: Majority of cases of vitiligo become apparent between the ages of _____ years.

Answer: 10 and 30

Flashcard 3: The pathologic basis of vitiligo is due to loss of _____.

Answer: melanocytes

Flashcard 4: Wood's lamp examination of vitiligo will show _____ fluorescence

Answer: milky-white

Flashcard 5: _____ Koebner phenomenon is seen in spontaneous repigmentation of vitiligo patches distant from the autologous skin graft sites, and with granuloma annulare

Answer: Remote reverse

Flashcard 6: Under Wood's lamp examination, lesions of vitiligo show a _____ fluorescence

Answer: ivory/milky white

Flashcard 7: Amongst autoimmune diseases, the strongest association of vitiligo is with _____

Answer: thyroid disorders

Flashcard 8: _____ phenomenon, defined as the development of lesions at sites of trauma to uninvolved skin of patients with cutaneous diseases is seen in vitiligo.

Answer: Koebner/Isomorphic

Flashcard 9: Freckles or ephelis are produced due to increased _____ production by melanocytes on exposure to UV rays

Answer: melanin

Flashcard 10: Poor prognostic factors for Vitiligo: - Positive family history - _____ vitiligo - Lesions over bony prominences - Leukotrichia - Koebner's/Isomorphic phenomenon - Nonsegmental vitiligo

Answer: Mucosal