Melanocyte Biology — Flashcards

Difference in proportion of _____ and Pheomelanin leads to difference in skin colours

Each melanocyte transfers melanosomes to _____ keratinocytes

_____ maybe seen in lichen planus as the melanin from epidermis gradually moves into the dermis as a result of degeneration of keratinocytes

In Systemic Sclerosis, local expression of _____ causes systemic release of a stem cell factor leading to diffuse hyperpigmentation

_____ method is the most specific method for staining melanin and stains it brown black

_____ pigment (carbon particles) are more resistant than the other pigments to transportation by the lymphatic system and thus, tend to persist in the skin

Albinism is associated with a _____ melanocyte count with decreased melanin production

What is the cause of skin pigmentation in hemosiderosis?_____

Freckles or ephelis are produced due to increased _____ production by melanocytes on exposure to UV rays

Poor prognostic factors for Vitiligo: - Positive family history - _____ vitiligo - Lesions over bony prominences - Leukotrichia - Koebner's/Isomorphic phenomenon - Nonsegmental vitiligo