Membrane Structure and Organization — Flashcards

Flashcard 1: The lipid molecules in the cell membrane are predominantly _____

Answer: phospholipids

Flashcard 2: Blood group antigens and cell surface receptors for cholera & tetanus toxins are made of what type of lipids?

Answer: Glycosphingolipids

Flashcard 3: In **Type II** membrane proteins, the **N-terminus** is located on the __________ side of the membrane.

Answer: Cytosolic (inside)

Flashcard 4: The **β (beta) subunit** of the Na+-K+ ATPase pump is a glycoprotein with one membrane-spanning domain and _____ glycosylation sites.

Answer: Three

Extra: The beta (β) subunit is essential for the proper assembly and membrane targeting of the catalytic alpha (α) subunit. It contains three N-glycosylation sites.

Flashcard 5: GLUT _____, found on Liver and Kidney is a urate transporter

Answer: 9

Flashcard 6: _____ is a phospholipid which is a component of the cell membrane and plays a key role in relationship to apoptosis.

Answer: Phosphatidylserine

Flashcard 7: The major GAG synthesized by arterial smooth muscle cells is _____, which binds LDL

Answer: dermatan sulfate

Flashcard 8: A _____ binding protein dynamin is involved in pinching off the vesicle formed in clathrin-mediated endocytosis

Answer: GTP

Flashcard 9: _____ are transmembrane glycoproteins that attach to extracellular matrix constituents such as laminin and fibronectin

Answer: Integrins

Flashcard 10: The phospholipid _____ is composed of phosphatidylcholine

Answer: lecithin