Membrane Disorders and Diseases — Flashcards

Flashcard 1: The major GAG synthesized by arterial smooth muscle cells is _____, which binds LDL

Answer: dermatan sulfate

Flashcard 2: GLUT _____, found on Liver and Kidney is a urate transporter

Answer: 9

Flashcard 3: _____ is a marker enzyme for plasma membrane

Answer: 5 Nucleotidase

Flashcard 4: Vibrio cholerae toxin acts on _____ ganglioside receptor on jejunal epithelial cells

Answer: GM1

Flashcard 5: Exocytosis involves two families of proteins: _____, which help vesicles dock onto the membrane, and SNAREs, which facilitate membrane fusion.

Answer: Rabs

Flashcard 6: Blood group antigens and cell surface receptors for cholera & tetanus toxins are made of what type of lipids?

Answer: Glycosphingolipids

Flashcard 7: The **β (beta) subunit** of the Na+-K+ ATPase pump is a glycoprotein with one membrane-spanning domain and _____ glycosylation sites.

Answer: Three

Extra: The beta (β) subunit is essential for the proper assembly and membrane targeting of the catalytic alpha (α) subunit. It contains three N-glycosylation sites.

Flashcard 8: A _____ binding protein dynamin is involved in pinching off the vesicle formed in clathrin-mediated endocytosis

Answer: GTP