Lipid Metabolism — Flashcards

The first step in all pathways of adrenocortical hormone synthesis is the conversion of _____ to pregnenolone by the enzyme cholesterol desmolase

Increased levels of cholesterol inside the hepatocyte leads to _____ activity of the enzyme HMG-CoA reductase

Once in the vicinity of the liver, the chylomicron remnant binds the _____ receptor via apoprotein E

Depletion of triglycerides from VLDLs produces _____, which may undergo further removal of triglycerides via the enzyme hepatic TG lipase, forming LDL

Pregnenolone may be converted to _____ via the enzyme 17-hydroxylase

Acetyl-CoA is converted to _____ via the enzyme HMG-CoA synthase (ketogenesis)

Triglycerides in chylomicrons are hydrolyzed by the enzyme _____, releasing free fatty acids

Apoprotein _____ binds the LDL receptor on the liver

In the ovaries, _____ cells synthesize and secrete progesterone from pregnenolone via the enzyme 3-hydroxysteroid dehydrogenase

The enzyme _____ may convert cholesterol to cholesterol ester in the blood in the presence of apoprotein A (found on HDL)