Lipid Metabolism — Flashcards

Pregnenolone may be converted to _____ via the enzyme 3-hydroxysteroid dehydrogenase

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of dihydroxyacetone phosphate -> _____, which combines with fatty acids to make triglycerides, leading to hepatosteatosis (liver pathology)

Acetyl-CoA carboxylase is inhibited by _____ and palmitoyl CoA

Decreased _____ or alteration in its metabolism results in mitochondrial dysfunction seen in Barth syndrome (cardioskeletal myopathy).

Free fatty acids (from triglycerides) can be used for energy by the _____ and skeletal muscle

In the intermembrane space, fatty acyl-CoA is converted to _____ via the enzyme carnitine palmitoyl transferase 1 (CPT1)

17-hydroxypregnenolone may be converted to _____ via the enzyme 3-hydroxysteroid dehydrogenase

17-hydroxyprogesterone may be converted to _____ via the enzyme 17,20-lyase

In preparation for β-oxidation, fatty acids are converted to _____ via the enzyme fatty acyl-CoA synthetase

Fatty acyl-CoA is broken down into molecules of _____ via the enzyme acyl-CoA dehydrogenase (β-oxidation)