Lipid Metabolism — Flashcards

Hormone sensitive lipase is stimulated by _____ and cortisol

A major step in the conversion of Arachidonic acids (AA) to leukotrienes is the conversion to _____ by the enzyme 5-lipooxygenase

In the intermembrane space, fatty acyl-CoA is converted to _____ via the enzyme carnitine palmitoyl transferase 1 (CPT1)

Decreased _____ or alteration in its metabolism results in mitochondrial dysfunction seen in Barth syndrome (cardioskeletal myopathy).

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of dihydroxyacetone phosphate -> _____, which combines with fatty acids to make triglycerides, leading to hepatosteatosis (liver pathology)

What are the three ketone bodies? 1. _____ 2. Beta-hydroxybutyrate 3. Acetone

17-hydroxypregnenolone may be converted to _____ via the enzyme 3-hydroxysteroid dehydrogenase

The enzyme _____, present in the endoplasmic reticulum, catalyzes the conversion of stearic acid (a saturated fatty acid) to oleic acid, which is a MUFA.

Abetalipoproteinemia is an _____ inherited malabsorption disorder that is caused by a mutation in the microsomal triglyceride transfer protein

_____ deficiency may cause dicarboxylic acidemia/aciduria due to omega-oxidation of fatty acids