Disorders of Iron Metabolism — Flashcards

Disorders of Iron Metabolism — Flashcards

Disorders of Iron Metabolism — Flashcards
#1

Primary _____ is due to mutations in the HFE gene on chromosome 6, leading to increased expression of DMT1 and decreased synthesis of Hepcidin

#2

_____ is a measure of transferrin molecules in the blood

#3

Hb _____ results from globin chain mutations that stabilize iron in the ferric state, leading to congenital methemoglobinemia.

#4

Some of the iron absorbed in the duodenum is taken up by _____ for storage as ferritin

#5

_____ iron (meat-derived) is readily absorbed and enters the duodenal cell via the heme transporter

#6

-thalassemia due to a _____ gene deletion is characterized by formation of 4 tetramers, known as Hb Barts

#7

_____ is the most commonly used indicator for iron in low anemic areas

#8

iron absorption inhibitors are _____

#9

total body iron is _____ gm

#10

1 gm of Hb contains _____ mg iron

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Disorders of Iron Metabolism Flashcards | Hemoglobin and Iron Metabolism Study Cards - OnCourse