Isoenzymes and Clinical Significance — Flashcards

Flashcard 1: _____ serves as the allosteric activator of muscle glycogen phosphorylase.

Answer: 5'AMP

Flashcard 2: Acid phosphatase and cathepsin are markers for _____

Answer: lysosome (cell organelle)

Flashcard 3: _____ are enzymes that catalyze the same reaction, but differ in AA sequence, Subunit composition, Electrophoretic mobility, Tissue localization and Substrate affinity

Answer: Isoenzymes

Flashcard 4: Which metal is a co-factor for alcohol dehydrogenase and carbonic anhydrase?

Answer: Zinc

Flashcard 5: Which LDH isozyme is found in the Brain, Kidney, Lungs, Spleen, pancreas?_____

Answer: LDH-3

Flashcard 6: _____ are a family of NAD-dependent protein deacetylases.

Answer: Sirtuins (Protein class)

Flashcard 7: Elevated _____ is the most common abnormal liver function test (LFT) in pyogenic liver abscess.

Answer: serum alkaline phosphatase (ALP) level (enzyme)

Flashcard 8: Sigmoid-shaped graph which is a property of _____ enzymes

Answer: multimeric

Flashcard 9: lead inhibits _____ and _____ enzymes

Answer: ALA dehydratase

Extra: 

Flashcard 10: When using an irreversible competitive inhibitor, the _____ changes, while the Km remains the same

Answer: Vmax