Malignant Hyperthermia — Flashcards

Flashcard 1: Cardiac arrhythmia is an _____ sign of malignant hyperthermia

Answer: early

Flashcard 2: Elevated end tidal carbon dioxide is an _____ sign of malignant hyperthermia

Answer: early

Flashcard 3: What is a major life-threatening anesthesia-related complication in patients with Duchenne muscular dystrophy?

Answer: Anesthesia-induced rhabdomyolysis (AIR) and Hyperkalemia

Extra: Patients with Duchenne muscular dystrophy (DMD) are at risk of Anesthesia-Induced Rhabdomyolysis (AIR) when exposed to triggering agents (volatile anesthetics or succinylcholine). This leads to acute, life-threatening hyperkalemia and potential cardiac arrest. Note: While the clinical presentation is similar, DMD is no longer considered a risk factor for classic Malignant Hyperthermia (MH). The two conditions have different genetic and pathophysiological bases.

Flashcard 4: Masseter spasm is an _____ sign of malignant hyperthermia

Answer: early

Flashcard 5: The following capnography waveform represents: _____

Answer: malignant hyperthermia

Flashcard 6: The following capnographic waveform is suggestive of _____:

Answer: Malignant hyperthermia

Flashcard 7: Tuberculin syringe 1ml or insulin syringe _____units, without fixed needle x3 are one of the components of the anaphylaxis kit

Answer: 40

Flashcard 8: Malignant hyperthermia is usually related to a defect in _____ receptors, which causes increased Ca2+ release from the SR

Answer: ryanodine

Flashcard 9: Propofol infusion syndrome is seen when the dose of propofol infusion is greater than _____ mg/kg/hour for 48 hours or longer

Answer: 4