Endocrine Pharmacology Practice Questions

Question 1

All of the following hormones have cell surface receptors except:

Accepted Answer

Thyroxine

Answer

Insulin

Answer

Adrenalin

Answer

Growth Hormone

Question 2

In which of the following situations is intensive management of diabetes typically avoided?

Accepted Answer

Diabetes with acute myocardial infarction

Answer

Stable diabetes with no complications

Answer

Diabetes in a well-controlled state

Answer

Diabetes with stable renal function post-transplant

Question 3

Treatment of choice in childhood thyrotoxicosis is:

Accepted Answer

Carbimazole

Answer

Radioiodine therapy

Answer

Surgical intervention

Answer

Lugol's iodine solution

Question 4

Which of the following statements best describes the mechanism of action of insulin on target cells?

Accepted Answer

Insulin binds to a transmembrane receptor on the outer surface of the plasma membrane, activating the tyrosine kinase in the cytosolic domain of the receptor.

Answer

Insulin binds to a receptor on the outer surface of the plasma membrane, activating adenylate cyclase through the Gs protein.

Answer

Insulin binds to a cytoplasmic receptor and is transferred as a hormone receptor complex to the nucleus to modulate gene expression.

Answer

Insulin enters the cell and causes the release of calcium ions from intracellular stores.

Question 5

Which of the following is the platinum-based chemotherapeutic agent used as first-line treatment for ovarian carcinoma?

Accepted Answer

Cisplatin

Answer

Cyclophosphamide

Answer

Methotrexate

Answer

Dacarbazine

Question 6

All the following  hormones have receptors on the plasma membrane of target tissues except:

Accepted Answer

Estradiol

Answer

Epinephrine

Answer

Glucagon

Answer

Thyrotropin

Question 7

A 30-year-old female complaints of fatigue and is unable to gain weight. On examination, her body felt warm. Which of the following investigation can be helpful in reaching the diagnosis?

Accepted Answer

Suppressed TSH with elevated thyroid hormone levels

Answer

Elevated TSH with normal thyroid hormone levels

Answer

Elevated TSH with low thyroid hormone levels

Answer

Normal TSH with abnormal thyroid hormone levels

Question 8

A 45-year-old man with a recent history of bizarre behavior is seen by a psychiatrist. On physical examination, the patient appears moderately obese with mild hypertension, facial acne, and fat accumulation in the supraclavicular fossae. Laboratory studies demonstrate neutrophilic leukocytosis, decreased lymphocytes, and absence of eosinophils, along with mild hypokalemia and mild metabolic alkalosis. The fasting serum glucose is within the reference range, but the OGTT shows glucose concentrations > 200 mg/dL. Laboratory studies also show a free urinary cortisol of 156 mg/24 hours. Which of the following questions would be of most help in establishing a diagnosis?

Accepted Answer

Are you receiving corticosteroids for some other disease?

Answer

Are you experiencing muscle weakness?

Answer

Do you have a family history of endocrine neoplasia?

Answer

Are you experiencing shortness of breath?

Question 9

Which of the following steroids possesses maximum glucocorticoid activity?

Accepted Answer

Dexamethasone

Answer

Prednisolone

Answer

Aldosterone

Answer

Cortisol

Question 10

Which of the following is recommended as the first-line pharmacological therapy for Type 2 diabetes mellitus?

Accepted Answer

Metformin

Answer

Acetohexamide

Answer

Glimepiride

Answer

Pioglitazone

Endocrine Pharmacology

Study Resources

Lessons

Questions

Flashcards

Lessons

Hypothalamic and Pituitary Hormones

Thyroid Drugs and Antithyroid Agents

Insulin and Oral Hypoglycemic Agents

Adrenocorticosteroids

Sex Hormones: Estrogens and Progestins

Androgens and Anabolic Steroids

Hormonal Contraceptives

Drugs Affecting Calcium Metabolism

Drugs for Osteoporosis

Pharmacological Management of Obesity

Practice Questions

Flashcards

About Endocrine Pharmacology for NEET-PG

Lessons in Endocrine Pharmacology

Master Endocrine Pharmacology