Drugs Affecting Blood and Blood Formation Practice Questions

Question 1

Which of the following is not a contraindication for the use of rtPA in stroke management?

Accepted Answer

Presence of coma

Answer

BP >185/110 mm Hg

Answer

Heparin in the past 24 hrs

Answer

Lesion occupying >1/3 of middle cerebral artery territory

Question 2

What is the mechanism of action of ticagrelor?

Accepted Answer

P2Y12 inhibitor

Answer

PAR1 activator

Answer

P2Y12 activator

Answer

PAR1 inhibitor

Question 3

Absolute contraindication to thrombolytic therapy is:

Accepted Answer

History of hemorrhagic stroke in past one year

Answer

Patients on nitrates

Answer

Hypertension

Answer

Pregnancy

Question 4

All of the following are antiplatelet agents except which of the following?

Accepted Answer

Tranexamic acid

Answer

Clopidogrel

Answer

Ticagrelor

Answer

Aspirin

Question 5

Which of the following is the platinum-based chemotherapeutic agent used as first-line treatment for ovarian carcinoma?

Accepted Answer

Cisplatin

Answer

Cyclophosphamide

Answer

Methotrexate

Answer

Dacarbazine

Question 6

Which of the following drugs is used for treatment of cancer associated thromboembolism?

Accepted Answer

LMW heparin

Answer

Direct factor Xa inhibitors

Answer

Warfarin

Answer

Anti-thrombin III inhibitors

Question 7

Arrange the following anticoagulant drugs in ascending order (shortest to longest) based on the pre-operative cessation time before surgery: 1) Clopidogrel 2) Ticlopidine 3) Low molecular weight heparin 4) Warfarin

Accepted Answer

3>4>1>2

Answer

2>1>3>4

Answer

4>3>2>1

Answer

3>4>2>1

Question 8

In which of the following clinical conditions does the use of anticoagulants provide maximum benefit?

Accepted Answer

Prevention of venous thrombosis and pulmonary embolism

Answer

Prevention of recurrences of myocardial infarction

Answer

Prevention of cerebrovascular accident (stroke)

Answer

Retinal artery thrombosis

Question 9

What is the mechanism of action of ticagrelor?

Accepted Answer

P2Y12 receptor antagonist

Answer

Cox inhibition

Answer

Inhibition of thromboxane synthase

Answer

GPIIb/IIIa inhibition

Question 10

A patient with a malignancy is undergoing chemotherapy. The platelet counts were reduced after the previous cycle of chemotherapy. Which of the following drugs can be used to treat this patient?

Accepted Answer

Oprelvekin (IL-11) - stimulates platelet production

Answer

Filgrastim - stimulates white blood cell production

Answer

Amifostine - protects against chemotherapy toxicity

Answer

Erythropoietin - stimulates red blood cell production

Drugs Affecting Blood and Blood Formation

Study Resources

Lessons

Questions

Flashcards

Lessons

Hematopoietic Growth Factors

Iron Preparations and Management of Iron Deficiency

Vitamin B12 and Folic Acid

Anticoagulants: Heparins and Direct Inhibitors

Oral Anticoagulants

Antiplatelet Drugs

Thrombolytic Agents

Hemostatic Drugs

Plasma Expanders

Blood Transfusion and Alternatives

Practice Questions

Flashcards

About Drugs Affecting Blood and Blood Formation for NEET-PG

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