Clinical Pharmacology and Drug Toxicity Practice Questions

Question 1

All are organophosphorus poisons, except.

Accepted Answer

Propoxur

Answer

Abate

Answer

Dibenanone

Answer

Malathion

Question 2

CSF sample is preserved for which poisoning?

Accepted Answer

Heavy metal

Answer

Organophosphates

Answer

Alcohol

Answer

Alphos

Question 3

A female was given morphine sulphate during labour for pain but she developed respiratory distress. Which of the following will be the correct antidote?

Accepted Answer

Naloxone

Answer

Epinephrine

Answer

Pralidoxime

Answer

Atropine

Question 4

A mother reports that her daughter ingested a substance in an unknown dose. The girl presents with hypertension, tachycardia, mydriasis, and hyperthermia. What is the most likely substance?

Accepted Answer

Cocaine

Answer

Heroin

Answer

Morphine

Answer

Chlorpheniramine

Answer

Organophosphate

Question 5

Which of the following is not used in the treatment of organophosphorus poisoning?

Accepted Answer

Naltrexone

Answer

Pralidoxime

Answer

Atropine

Answer

Activated charcoal

Question 6

A patient presented to the emergency department with an overdose of a drug, exhibiting increased salivation and increased bronchial secretions. On examination, the blood pressure was 88/60 mmHg, and the RBC cholinesterase level was reduced to 50% of normal. What should be the treatment for this individual?

Accepted Answer

Atropine

Answer

Physostigmine

Answer

Flumazenil

Answer

Neostigmine

Question 7

What is the primary cause of death in Neuroleptic Malignant Syndrome?

Accepted Answer

None of the options

Answer

Respiratory failure

Answer

Liver failure

Answer

Drug toxicity

Question 8

A 34-year-old rickshaw puller who has been using heroin for the past 10 years was found unconscious by his family members and brought to the casualty. On examination, he exhibited bradycardia, shallow breathing, constricted pupils, a blood pressure of 100/70 mmHg, brisk bilateral deep tendon reflexes, and flexor plantar reflexes on both sides. Which is the best treatment for him?

Accepted Answer

Naloxone

Answer

Buprenorphine

Answer

Flumazenil

Answer

Methadone

Question 9

A 5-year-old child who has taken 10 iron tablets presents with nausea and abdominal pain. What is the antidote of iron poisoning?

Accepted Answer

Deferoxamine

Answer

EDTA

Answer

British Anti Lewisite

Answer

Penicillamine

Question 10

A comatose person is brought to the hospital. On examination his respiratory rate is 8 / min with pulse rate of 75 bpm with BP of 110 / 70 mm Hg. His Pupils are shown below. Body temperature is 96°F. What is the probable diagnosis?

Accepted Answer

Opioid overdose

Answer

Uncal herniation

Answer

Pontine stroke

Answer

Metabolic encephalopathy

Clinical Pharmacology and Drug Toxicity

Study Resources

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Principles of Clinical Pharmacology

Therapeutic Drug Monitoring

Drug Toxicity and Overdose

Antidotes and Their Applications

Management of Drug Poisoning

Drug-Induced Liver Injury

Drug-Induced Kidney Injury

Drug-Induced Blood Dyscrasias

Drug-Induced QT Prolongation

Pharmacovigilance

Practice Questions

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About Clinical Pharmacology and Drug Toxicity for NEET-PG

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