Antimicrobial Agents Practice Questions

Question 1

Which of the following is NOT a mechanism of antibiotic resistance?

Accepted Answer

Increased drug absorption

Answer

Efflux pump activity

Answer

Inactivation by enzymes such as beta-lactamase

Answer

Modification of drug target sites

Question 2

Which of the following statements about the biodisposition of penicillins and cephalosporins is NOT accurate?

Accepted Answer

Renal tubular reabsorption of beta-lactams is inhibited by probenecid

Answer

Procaine penicillin G is used for intramuscular injection

Answer

Nafcillin and ceftriaxone are eliminated mainly by biliary secretion

Answer

Oral bioavailability is affected by lability to gastric acid

Question 3

Match List-I with List-II and select the correct answer using the code given below the Lists:

Accepted Answer

A→3  B→4  C→2  D→1

Answer

A→1  B→2  C→4  D→3

Answer

A→3  B→2  C→4  D→1

Answer

A→1  B→4  C→2  D→3

Question 4

Empirical drug of choice for treatment of meningococcal meningitis is:-

Accepted Answer

Ceftriaxone

Answer

Cefotetan

Answer

Cefoxitin

Answer

Gentamicin

Question 5

Which of the following is not indicated for the treatment of anaerobic infections?

Accepted Answer

Gentamicin

Answer

Piperacillin-tazobactam

Answer

Metronidazole

Answer

Clindamycin

Question 6

Which of the following statements about cephalosporins is false?

Accepted Answer

Cefoxitin has no activity against anaerobes.

Answer

Cefoperazone has got antipseudomonal effect.

Answer

Cephalosporins act by inhibiting cell wall synthesis.

Answer

Ceftazidime is a 3rd generation cephalosporin.

Question 7

Drugs of choice for MRSA in skin and soft tissue infections are:

Accepted Answer

Vancomycin, Linezolid

Answer

Clindamycin, Vancomycin

Answer

Vancomycin, Teicoplanin

Answer

Dicloxacillin, Vancomycin

Question 8

Burkholderia cepacia is resistant to which of the following antibiotics?

Accepted Answer

Cefotetan

Answer

Trimethoprim-sulfamethoxazole

Answer

Ceftazidime

Answer

Temocillin

Question 9

On chronic use, linezolid leads to which of the following?

Accepted Answer

Thrombocytopenia

Answer

Deranged LFT

Answer

Nephrotoxicity

Answer

Ototoxicity

Question 10

Continued suppression of bacterial growth after antibiotic levels have fallen below the Minimum Inhibitory Concentration (MIC) is known as?

Accepted Answer

Post antibiotic effect

Answer

Time dependent killing

Answer

Sequential blockade

Answer

Concentration dependent killing

Antimicrobial Agents

Study Resources

Lessons

Questions

Flashcards

Lessons

Beta-Lactam Antibiotics

Aminoglycosides

Macrolides and Ketolides

Tetracyclines

Quinolones

Sulfonamides and Trimethoprim

Antimycobacterial Drugs

Antifungal Agents

Antiviral Drugs

Antiparasitic Agents

Principles of Antimicrobial Selection

Antimicrobial Resistance

Practice Questions

Flashcards

About Antimicrobial Agents for NEET-PG

Lessons in Antimicrobial Agents

Master Antimicrobial Agents