Hematology Practice Questions

Question 1

Which of the following is the most common myeloproliferative disorder?

Accepted Answer

Essential Thrombocythemia

Answer

Polycythemia rubra vera

Answer

CML

Answer

Myelofibrosis

Question 2

Which is the cell of origin of Chronic Lymphocytic Leukaemia / Small Lymphocytic Lymphoma?

Accepted Answer

Naïve B cells

Answer

Mature B cells

Answer

Progenitor T cells

Answer

Mature T cells

Question 3

What is the typical bone marrow finding in myelofibrosis?

Accepted Answer

Dry tap (hypocellular)

Answer

Megaloblastic cells

Answer

Microcytic cells

Answer

Thrombocytosis

Question 4

Which of the following are neonatal complications of maternal diabetes during pregnancy?
I. Hyperbilirubinemia
II. Hypocalcemia
III. Cardiomyopathy
IV. Hypoglycemia

Select the correct answer using the code given below :

Accepted Answer

I, II and IV

Answer

I, II and III

Answer

II, III and IV

Answer

I, III and IV

Question 5

A newborn presents with the clinical features shown in the image below. What is the most likely diagnosis?

Accepted Answer

Trisomy 18

Answer

Trisomy 21

Answer

Trisomy 13

Answer

Trisomy 12

Question 6

A 10-month-old child with coarse facies is referred for developmental delay. On examination, hepatosplenomegaly was noted. WBC N-acetylglucosamine-1-phosphotransferase activity was absent. The X-ray is shown below. What is the diagnosis?

Accepted Answer

I cell disease

Answer

MPS type II

Answer

Proteus syndrome

Answer

Larsen syndrome

Question 7

A 5 year old child presented with periorbital swelling and oliguria. Nephrotic syndrome is suspected. Which of the following is the commonest type of nephrotic syndrome in this child?

Accepted Answer

Minimal change disease

Answer

Focal segmental glomerulosclerosis (FSGS)

Answer

Chronic glomerulonephritis

Answer

Congenital nephrotic syndrome

Question 8

A 5-year-old boy presents with petechial bleeding and bruising on his torso and limbs. He has no other signs or symptoms and does not appear ill. His mother reports a gastrointestinal infection several weeks prior to the onset of petechiae and bruising. Complete blood count reveals thrombocytopenia (<20 x 10^9/L), with other parameters within the expected range for his age. Prothrombin time, partial thromboplastin time, and metabolic panels are all within the reference range. What is the expected outcome of this blood disorder?

Accepted Answer

Complete resolution is expected.

Answer

Survival rate is up to 70% depending on risk stratification.

Answer

Lifelong disease dependent on factor VIII substitution.

Answer

Lifelong disease dependent on factor IX substitution.

Question 9

A 9-year-old girl develops widespread pinpoint skin hemorrhages after recovering from a flu-like illness 1 week earlier. Laboratory findings reveal a platelet count of 20,000/mL with no other abnormalities. Her bone marrow shows an increased number of megakaryocytes. The platelet count is normal after 2 months. Which of the following is the appropriate diagnosis?

Accepted Answer

Idiopathic thrombocytopenic purpura

Answer

Antiphospholipid antibody syndrome

Answer

Disseminated intravascular coagulation

Answer

Hemolytic-uremic syndrome

Question 10

A patient presents with ecchymoses and petechiae all over the body and no hepatosplenomegaly. Which of the following statements is NOT true?

Accepted Answer

Bleeding into the joints

Answer

Increased megakaryocytes in bone marrow

Answer

Decreased platelets in blood

Answer

Disease resolves itself in 80% of patients in 2-6 weeks

Hematology

Study Resources

Lessons

Questions

Flashcards

Lessons

Anemias in Children

Hemoglobinopathies

Hemolytic Anemias

Nutritional Anemias

Thrombocytopenia

Bleeding Disorders

Thrombotic Disorders

White Blood Cell Disorders

Bone Marrow Failure Syndromes

Blood Component Therapy

Hemophilia and Von Willebrand Disease

Evaluation of Bleeding Tendencies

Practice Questions

Flashcards

About Hematology for NEET-PG

Lessons in Hematology

Master Hematology