Immunopathology Practice Questions

Question 1

Given the immunologic abnormalities of normal serum IgG, normal serum IgA, normal serum IgM, decreased T-cell function, and decreased parathyroid function, which clinical presentation is most likely?

Accepted Answer

A distinctive-appearing 8-month-old boy with an interrupted aortic arch, hypocalcemia, and cleft palate

Answer

A 1-year-old boy with severe eczema, recurrent middle-ear infections, lymphopenia, and thrombocytopenia

Answer

A 9-year-old boy with an eczema-like rash and recurrent severe staphylococcal infections

Answer

A 5-year-old boy who, after 3 months of age, developed recurrent otitis media, pneumonia, diarrhea, and sinusitis, often with simultaneous infections at two or more disparate sites

Question 2

In primary immune deficiency, the following plasma protein fraction can be reduced:

Accepted Answer

Gamma globulin

Answer

Alpha2 globulin

Answer

Alpha1 globulin

Answer

Beta globulin

Question 3

Which of the following is not a first-line drug for the management of a patient with rheumatoid arthritis?

Accepted Answer

Azathioprine

Answer

Hydroxychloroquine

Answer

Sulfasalazine

Answer

Methotrexate

Question 4

Which of the following are correct in respect of Systemic Inflammatory Response Syndrome (SIRS)?

1. It is caused by the release of lipopolysaccharide endotoxin from dying E. coli bacteria.
2. It is same as bacteraemia.
3. It results in Multiple Organ Dysfunction Syndrome (MODS).
4. White cell counts of more than 12 × 10^9/litre are present. Select the answer using the code given below.

Accepted Answer

1, 3 and 4

Answer

2, 3 and 4

Answer

1, 2 and 3

Answer

1, 2 and 4

Question 5

Statement 1 - A 59-year-old patient presents with flaccid bullae. Histopathology shows a suprabasal acantholytic split.
Statement 2 - The row of tombstones appearance is diagnostic of Pemphigus vulgaris.

Accepted Answer

Statements 1 & 2 are correct, 2 is not explaining 1

Answer

Statements 1 and 2 are correct and 2 is the correct explanation for 1

Answer

Statements 1 and 2 are incorrect

Answer

Statement 1 is incorrect

Question 6

What is the Rose Waaler test used for?

Accepted Answer

Passive hemagglutination test

Answer

Ring precipitation

Answer

Precipitation in gel

Answer

Complement fixation test

Question 7

All are true about autoimmune disease except:

Accepted Answer

Higher incidence among males

Answer

T cells recognize self-antigen

Answer

Polyclonal B cell activation

Answer

Hashimoto's thyroiditis is an example

Question 8

First mediator of inflammation to be released is

Accepted Answer

Histamine

Answer

Nitric oxide

Answer

PAF

Answer

IL-1

Question 9

What is the definitive method for diagnosing Pneumocystis jirovecii pneumonia?

Accepted Answer

Finding cysts in tissue specimens

Answer

Serological test

Answer

Chest X-ray

Answer

CT scan of thorax

Question 10

Absence of differentiation is known as:-

Accepted Answer

Anaplasia

Answer

Dysplasia

Answer

Metaplasia

Answer

Hyperplasia

Immunopathology

Study Resources

Lessons

Questions

Flashcards

Lessons

Cells and Tissues of the Immune System

Innate Immunity

Adaptive Immunity

Hypersensitivity Reactions

Autoimmune Diseases

Immunodeficiency Disorders

Transplantation Immunopathology

Immune Response to Infections

Immunologic Laboratory Techniques

Tumor Immunology

Practice Questions

Flashcards

About Immunopathology for NEET-PG

Lessons in Immunopathology

Master Immunopathology