General Microbiology Practice Questions

Question 1

Which of the following is NOT a mechanism of antibiotic resistance?

Accepted Answer

Increased drug absorption

Answer

Efflux pump activity

Answer

Inactivation by enzymes such as beta-lactamase

Answer

Modification of drug target sites

Question 2

It is true regarding normal microbial flora present on skin and mucous membrane that

Accepted Answer

It is difficult to permanently eradicate by antimicrobial agents

Answer

It is absent in the stomach due to acidic pH

Answer

It establishes in the body only after the neonatal period

Answer

The flora in the small bronchi is similar to that of the trachea

Question 3

Blood culture is positive in which infection caused by Staphylococcus aureus?

Accepted Answer

Infective endocarditis

Answer

Impetigo

Answer

Toxic Shock Syndrome (TSS)

Answer

Staphylococcal Scalded Skin Syndrome (SSSS)

Question 4

A 25-year-old woman presents with a sudden onset of high fever, chills, and rigors. Blood cultures are pending. What is the next appropriate step in her management?

Accepted Answer

Administer broad-spectrum antibiotics

Answer

Wait for blood culture results

Answer

Start antipyretic therapy only

Answer

Order a CT scan

Question 5

A farmer presents with pustules that show Gram-positive cocci on smear. The culture shows beta hemolysis, and the organisms are catalase-negative. To confirm that the identified organism is group A streptococcus, which of the following tests should be performed?

Accepted Answer

Bacitracin sensitivity

Answer

Novobiocin sensitivity

Answer

Bile solubility

Answer

Optochin sensitivity

Question 6

Gram stain of CSF shows gram-negative diplococci. Culture grows on Thayer-Martin medium. Most likely organism?

Accepted Answer

N. meningitidis

Answer

L. monocytogenes

Answer

S. pneumoniae

Answer

H. influenzae

Question 7

All of the following statements about Staphylococcus aureus are true, except:

Accepted Answer

Most common source of infection is cross infection from infected people.

Answer

About 30% of general population is healthy nasal carriers.

Answer

Methicillin resistance is chromosomally mediated.

Answer

Epidermolysin and TSS toxin are superantigens.

Question 8

A patient presented with meningitis, and the CSF sample was subjected to gram staining and microscopy and appears as shown in the microscopic image given below. Which of the following features / tests will be characteristic of the organism?

Accepted Answer

Catalase negative, optochin sensitive.

Answer

Ferments glucose and maltose but not inulin

Answer

Oxidase and catalase negative, does not ferment inulin

Answer

Oxidase and catalase positive and does not ferment maltose or glucose

Question 9

A 9-year-old child presented to OPD with complaints of high-grade fever, vomiting, and one episode of seizure. CSF examination was done and Gram staining of the culture showed lanceolate-shaped gram-positive diplococci. What is the probable causative agent?

Accepted Answer

Streptococcus pneumoniae

Answer

Haemophilus influenzae

Answer

Streptococcus agalactiae

Answer

Neisseria meningitidis

Question 10

A 2-year-old child presents with fever for 5 days and fast breathing. On examination breath sounds are reduced in left infra-axillary areas and left inframammary areas. CXR was performed and pleural tap was done. Gram stain of pus drained in pleural tap shows: (Recent NEET Pattern 2016-17)

Accepted Answer

Pneumococcus

Answer

Meningococcus

Answer

Staphylococcus

Answer

Enterococcus

General Microbiology

Study Resources

Lessons

Questions

Flashcards

Lessons

History and Scope of Microbiology

Classification of Microorganisms

Bacterial Morphology and Structure

Bacterial Physiology and Metabolism

Bacterial Genetics

Microbial Growth and Nutrition

Sterilization and Disinfection

Bacterial Identification Methods

Normal Microbiota and Pathogenicity

Antimicrobial Susceptibility Testing

Practice Questions

Flashcards

About General Microbiology for NEET-PG

Lessons in General Microbiology

Master General Microbiology