Hemoglobin and Iron Metabolism Practice Questions

Question 1

Which of the following is the most sensitive and specific test during antenatal check-up for a pregnant lady with family history of Thalassemia?

Accepted Answer

High performance liquid chromatography

Answer

P. smear and reticulocyte count

Answer

Hemoglobin electrophoresis

Answer

NESTROFT

Question 2

A child presents with recurrent chest infections and abdominal pain. There is a history of 1    blood transfusion in the past. On examination, he had icterus and mild splenomegaly.    Electrophoresis shows increased HbA2, HbF, and S spike. What is the likely diagnosis?

Accepted Answer

Sickle Beta Thalassemia

Answer

HbC disease

Answer

Sickle cell disease

Answer

Aplastic anemia

Question 3

Which is/are the correct statements regarding the cut off points for the diagnosis of anaemia?

1. Haemoglobin for adult males is 13 g/dl

2. Haemoglobin for adult non-pregnant female is 12 g/dl

3. Haemoglobin for adult pregnant female is 11 g/dl

4. Haemoglobin for children six months to six years of age is 11 g/dl
Select the correct answer using the code given below:

Accepted Answer

1, 2, 3 and 4

Answer

1 and 3 only

Answer

1 only

Answer

2 and 4 only

Question 4

O2 (Oxygen) dissociation curve is shifted to right in the following except

Accepted Answer

Metabolic alkalosis

Answer

Hypercapnia

Answer

Rise in temperature

Answer

Raised 2, 3 DPG level

Question 5

Haemoglobin, unlike myoglobin, demonstrates a unique characteristic in its oxygen binding.

Accepted Answer

Co-operative effect of combined O2

Answer

Parabolic curve of oxygen association

Answer

Co-operative index of 81

Answer

Hill's coefficient of 1

Question 6

Which physiological adaptation does not happen at high altitudes?

Accepted Answer

Respiratory acidosis

Answer

Pulmonary vasoconstriction

Answer

Hypoxia

Answer

Polycythemia

Question 7

Which of the following is the LEAST likely indication for intravenous iron administration?

Accepted Answer

Patients on Erythropoietin Therapy

Answer

Inability to Tolerate oral Iron

Answer

Iron malabsorption

Answer

Intermittent Gastrointestinal blood loss

Question 8

All of the following are true about glutathione, except:

Accepted Answer

It converts hemoglobin to methemoglobin

Answer

It is co-factor of various enzymes

Answer

It is a tripeptide

Answer

It conjugates xenobiotics

Question 9

Which of the following is true about alpha-1 antitrypsin?

Accepted Answer

Inhibits elastase

Answer

Inhibits trypsin

Answer

Inhibits chymotrypsin

Answer

Inhibits trypsinogen activation

Question 10

In G6PD deficiency, which enzyme's function is MOST directly impaired due to decreased NADPH availability, leading to reduced protection against oxidative stress?

Accepted Answer

Glutathione reductase

Answer

Catalase

Answer

Pyruvate kinase

Answer

Superoxide dismutase

Hemoglobin and Iron Metabolism

Study Resources

Lessons

Questions

Flashcards

Lessons

Hemoglobin Structure and Function

Oxygen Transport and Oxygen-Hemoglobin Dissociation Curve

Hemoglobin Variants and Hemoglobinopathies

Thalassemias

Methemoglobin and Abnormal Hemoglobins

Hemoglobin Synthesis

Heme Synthesis and Porphyrias

Iron Absorption and Transport

Iron Storage and Recycling

Disorders of Iron Metabolism

Anemia: Biochemical Aspects

Biochemistry of Hemostasis

Practice Questions

Flashcards

About Hemoglobin and Iron Metabolism for NEET-PG

Lessons in Hemoglobin and Iron Metabolism

Master Hemoglobin and Iron Metabolism