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Ask Rezzy/Cardiology: valvular heart disease — murmurs, diagnosis and management

Cardiology: valvular heart disease — murmurs, diagnosis and management

RezzyRezzy

Valvular heart disease is a huge part of cardiology and a favorite for the USMLE! It basically boils down to two problems: the valve doesn't open enough (stenosis) or it doesn't close properly (regurgitation).

To get us started, I've put together a quick reference table for the "Big Four" murmurs you'll definitely see on your exams.

Valve LesionTimingDescriptionKey Physical Exam Findings
Aortic Stenosis (AS)SystolicCrescendo-decrescendoRadiates to carotids; Pulsus parvus et tardus
Mitral Regurgitation (MR)SystolicHolosystolic, blowingRadiates to axilla; often post-MI or MVP
Aortic Regurgitation (AR)DiastolicEarly decrescendo, blowingWide pulse pressure; Water-hammer pulse
Mitral Stenosis (MS)DiastolicMid-to-late rumblingOpening snap; often due to Rheumatic Fever

That table covers the basics, but there's a lot more to management—like knowing when to move from medical therapy to surgical intervention (TAVR vs. SAVR for Aortic Stenosis, for example).

Let me find some detailed lessons that break down the diagnostic algorithms and management guidelines for you.

Those lessons will give you the deep dive you need for the pathophysiology and management.

One of the trickiest parts of these questions is identifying the murmur based on where the stethoscope is placed. I'll pull up a diagram showing the classic auscultation points to help you visualize where each valve is best heard.

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