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Ask Rezzy/Pulmonary embolism: Wells score, CTPA findings and anticoagulation

Pulmonary embolism: Wells score, CTPA findings and anticoagulation

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Pulmonary embolism (PE) is a classic "can't miss" diagnosis for the AKT. It's all about risk stratification, knowing when to pull the trigger on imaging, and starting the right anticoagulation.

Let's start with the Wells Score, which helps us decide if a PE is clinically likely or unlikely.

Wells Score for Pulmonary Embolism

The Wells score is the most commonly used clinical prediction rule. For the AKT, you should be familiar with the two-level version used to guide the next steps in management.

Clinical FeaturePoints
Clinical signs and symptoms of DVT (minimum of leg swelling and pain with palpation of the deep veins)3.0
PE is #1 diagnosis OR as likely as any other diagnosis3.0
Heart rate > 100 beats per minute1.5
Immobilization (at least 3 days) or surgery in the previous 4 weeks1.5
Previous objectively diagnosed PE or DVT1.5
Hemoptysis1.0
Malignancy (on treatment, treated in the last 6 months, or palliative)1.0

Interpretation (Two-level PE Wells Score):

  • PE Likely (> 4 points): Arrange an immediate CT Pulmonary Angiogram (CTPA). If there's a delay, start interim anticoagulation.
  • PE Unlikely (≤ 4 points): Arrange a D-dimer test. If positive, arrange a CTPA (and interim anticoagulation if the CTPA is delayed).

I'll put this into a clear table format for you to reference easily.

Wells Score ResultClinical ProbabilityRecommended Action
> 4 pointsPE LikelyImmediate CTPA (Interim anticoagulation if delay)
≤ 4 pointsPE UnlikelyPerform D-dimer test
D-dimer Positive-Arrange CTPA (Interim anticoagulation if delay)
D-dimer Negative-PE unlikely; consider alternative diagnosis

When we move to imaging, the CT Pulmonary Angiogram (CTPA) is the gold standard. The key finding you're looking for is a filling defect—this is where the contrast (which looks bright white) is blocked by a clot (which looks dark grey or black) within the pulmonary arteries.

Let me find a clear image of what that looks like for you.

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