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Ask Rezzy/Prescribing errors: common mistakes, high-risk drugs and safe prescribing principles

Prescribing errors: common mistakes, high-risk drugs and safe prescribing principles

RezzyRezzy

Prescribing is a huge part of the UKMLA AKT, and honestly, it's one of the most practical skills you'll take onto the wards. It's not just about knowing the drug; it's about getting the details right every single time to ensure patient safety.

Common Prescribing Mistakes

Even the most experienced clinicians can slip up. Here are the most frequent "traps" seen in exams and clinical practice:

  • Dosing Errors: The classic "10-fold error" (e.g., writing 10mg instead of 1mg). This often happens when mixing up micrograms and milligrams.
  • Allergy Oversight: Prescribing a penicillin-based antibiotic (like Co-amoxiclav) to a patient with a documented anaphylactic reaction to Penicillin.
  • Illegibility: In paper-based systems, poor handwriting leads to nurses misinterpreting the drug or dose.
  • Incomplete Orders: Forgetting to specify the route (e.g., IV vs. PO) or the frequency (e.g., PRN vs. BD).
  • Drug Interactions: Missing a significant interaction, such as prescribing a Macrolide (Clarithromycin) to a patient already on Simvastatin (risk of rhabdomyolysis).

To help you keep track of the "heavy hitters," I've put together a table of high-risk medications that frequently appear in AKT safety questions.

Drug ClassKey RisksEssential Safety Tip
Anticoagulants (e.g., Warfarin)Major haemorrhageAlways check the most recent INR before prescribing.
InsulinSevere hypoglycaemiaNever abbreviate "units" to "U". Always write it in full.
MethotrexateBone marrow suppression / HepatotoxicityPrescribed ONCE WEEKLY. Co-prescribe Folic Acid (usually 5mg).
Aminoglycosides (e.g., Gentamicin)Nephrotoxicity & OtotoxicityRequires strict therapeutic drug monitoring (TDM) and renal function checks.
OpioidsRespiratory depression / ToxicityUse extreme caution when switching between different opioids (e.g., Morphine to Oxycodone).
NSAIDsGI bleed / Renal impairmentAvoid in patients with CKD, peptic ulcers, or severe heart failure.

Safe prescribing isn't just about avoiding mistakes; it's about building a robust system for every prescription you write. The "5 Rights" are the gold standard for this:

  1. Right Patient: Always check the name, DOB, and hospital number.
  2. Right Drug: Double-check the spelling (e.g., Amlodipine vs. Amitriptyline).
  3. Right Dose: Is it appropriate for their age, weight, and renal function?
  4. Right Route: Can they swallow? Do they need it IV for faster action?
  5. Right Time: Is it a once-daily (OD), twice-daily (BD), or three-times-daily (TDS) medication?

I've created a quick mental checklist you can use before signing any prescription.

That flowchart is a great way to visualize the process, especially when you're in a busy clinical environment. For the UKMLA AKT, you'll often be asked to identify the next best step when a prescribing error is found, or to choose the safest option for a patient with specific comorbidities (like renal impairment).

Let me find some high-yield lessons that cover these prescribing principles in more detail for your exam prep.

Those lessons on renal dosing and polypharmacy are particularly high-yield for the AKT, as they often form the basis of complex prescribing scenarios.

One final tip: Always use the BNF (British National Formulary). In the AKT, you'll have access to it, and in real life, it's your safety net. If you're ever unsure about a dose or an interaction, look it up. It's better to take 30 seconds to check than to make a mistake that could harm a patient.

Would you like to try a quick quiz to see how well you can spot these prescribing pitfalls?

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