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Ask Rezzy/Basic dermatology: primary and secondary skin lesions terminology

Basic dermatology: primary and secondary skin lesions terminology

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Dermatology is often called the "visual specialty" because so much of the diagnosis depends on accurately describing what you see. We divide skin lesions into primary (the initial physical change) and secondary (changes that occur due to evolution, trauma, or infection of a primary lesion).

Let's start with the primary lesions, which are the building blocks of any skin exam.

Lesion TypeDescriptionExamples
MaculeFlat, non-palpable change in color, < 1 cmFreckles, Petechiae
PatchFlat, non-palpable change in color, > 1 cmVitiligo, Melasma
PapuleSolid, raised lesion, < 1 cmAcne, Warts
PlaqueRaised, flat-topped lesion, > 1 cmPsoriasis
NoduleSolid, deep-seated raised lesion, > 1 cmLipoma, Erythema nodosum
VesicleFluid-filled (serous), < 1 cmHerpes simplex, Chickenpox
BullaFluid-filled (serous), > 1 cmBullous pemphigoid
PustulePus-filled vesicleAcne pustule, Folliculitis
WhealTransient, edematous papule or plaqueUrticaria (Hives)

Secondary lesions are what happens when a primary lesion is scratched, infected, or simply ages. They are crucial for understanding the chronicity of a skin condition.

Lesion TypeDescriptionExamples
ScaleFlaking or shedding of the stratum corneumPsoriasis, Dandruff
CrustDried serum, blood, or pus (a "scab")Impetigo (honey-colored)
ErosionLoss of part of the epidermis; heals without scarringRuptured vesicle
UlcerLoss of epidermis and part of dermis; heals with scarringPressure sore, Syphilis
FissureLinear crack in the skinAthlete's foot, Cheilitis
AtrophyThinning of the skin (parchment-like)Topical steroid overuse
LichenificationThickening of skin with accentuated markings from rubbingChronic eczema
ExcoriationLinear erosion caused by scratchingScabies, Neurodermatitis
ScarReplacement of normal skin with fibrous tissuePost-surgical, Keloid

Visualizing these differences is key to mastering dermatology. Let me find a diagram that illustrates these primary and secondary lesions for you.

This diagram provides a clear cross-sectional view of how these lesions sit within the layers of the skin, which is very helpful for understanding their depth.

Dermatologic lesions diagram showing primary and secondary skin lesions

To dive deeper into how these lesions present in specific diseases, I've pulled up some relevant lessons for you.

Mastering these terms is the first step in any dermatology rotation. If you'd like to practice identifying these in clinical scenarios or want to see more specific examples of conditions like psoriasis or impetigo, just let me know!

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