Gastrointestinal perforationDownloads

A 66-year-old man is brought to the emergency department after a motor vehicle accident. The patient was a restrained passenger in a car that was struck on the passenger side while crossing an intersection. In the emergency department, he is alert and complaining of abdominal pain. He has a history of hyperlipidemia, gastroesophageal reflux disease, chronic kidney disease, and perforated appendicitis for which he received an interval appendectomy four years ago. His home medications include rosuvastatin and lansoprazole. His temperature is 99.2°F (37.3°C), blood pressure is 120/87 mmHg, pulse is 96/min, and respirations are 20/min. He has full breath sounds bilaterally. He is tender to palpation over the left 9th rib and the epigastrium. He is moving all four extremities. His FAST exam reveals fluid in Morrison's pouch. This patient is most likely to have which of the following additional signs or symptoms?

A 52-year-old man is brought to the emergency department with severe epigastric discomfort and left-sided chest pain radiating to the back that began after waking up. He has also vomited several times since the pain began. He underwent an esophagogastroduodenoscopy the previous day for evaluation of epigastric pain. He has ischemic heart disease and underwent a coronary angioplasty 3 years ago. His mother died of pancreatic cancer when she was 60 years old. His current medications include aspirin, clopidogrel, metoprolol, ramipril, and rosuvastatin. He is pale, anxious, and diaphoretic. His temperature is 37.9°C (100.2°F), pulse is 140/min, respirations are 20/min, and blood pressure is 100/60 mm Hg in his upper extremities and 108/68 mm Hg in his lower extremities. Pulse oximetry on room air shows oxygen saturation at 98%. An S4 is audible over the precordium, in addition to crepitus over the chest. Abdominal examination shows tenderness to palpation in the epigastric area. Serum studies show an initial Troponin I level of 0.031 ng/mL (N < 0.1 ng/mL) and 0.026 ng/mL 6 hours later. A 12-lead ECG shows sinus tachycardia with nonspecific ST-T changes. Which of the following is the most likely diagnosis?