A 37-year-old woman presents to the general medical clinic with a chief complaint of anxiety. She has been having severe anxiety and fatigue for the past seven months. She has difficulty concentrating and her work has suffered, and she has also developed diarrhea from the stress. She doesn't understand why she feels so anxious and is unable to attribute it to any specific aspect of her life right now. You decide to begin pharmacotherapy. All of the following are suitable mechanisms of drugs that can treat this illness EXCEPT:
AA drug that stimulates 5-HT1A receptors
BA drug that blocks dopamine 2 receptors
CA drug that acts as a GABA agonist
DA drug that blocks 5-HT reuptake
EA drug that blocks both serotonin and norepinephrine reuptake
A 31-year-old woman is brought to the emergency department by EMS, activated by a bystander who found her wandering in the street. She provides short, vague answers to interview questions and frequently stops mid-sentence and stares at an empty corner of the room, appearing distracted. Her affect is odd but euthymic. Past medical history is notable for obesity and pre-diabetes. Collateral information from her brother reveals that she left home 3 days ago because she thought her family was poisoning her and has since been listed as a missing person. He also describes a progressive 2-year decline in her social interactions and self-care. The patient has no history of substance use and has never been prescribed psychiatric medications before but is amenable to starting a medication now. Which of the following would be the most appropriate as a first line medication for her?
ARisperidone
BTrazodone
CClomipramine
DOlanzapine
EClozapine
A 45-year-old obese man is evaluated in a locked psychiatric facility. He was admitted to the unit after he was caught running through traffic naked while tearing out his hair. His urine toxicology screening was negative for illicit substances and after careful evaluation and additional history, provided by his parents, he was diagnosed with schizophrenia and was treated with aripiprazole. His symptoms did not improve after several dosage adjustments and he was placed on haloperidol, but this left him too lethargic and slow and he was placed on loxapine. After several dosage adjustments today, he is still quite confused. He describes giant spiders and robots that torture him in his room. He describes an incessant voice screaming at him to run away. He also strongly dislikes his current medication and would like to try something else. Which of the following is indicated in this patient?
AHaloperidol
BOlanzapine
CChlorpromazine
DFluphenazine
EClozapine
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