Which factor most strongly influences protein filtration at the glomerulus?
AElectrical charge
BMolecular size
CShape
DTemperature
A 62-year-old man comes to the physician for a follow-up examination. One month ago, therapy with lisinopril was initiated for treatment of hypertension. His blood pressure is 136/86 mm Hg. Urinalysis shows a creatinine clearance of 92 mL/min. The patient's serum creatinine concentration is most likely closest to which of the following values?
A1.7 mg/dL
B1.1 mg/dL
C2.0 mg/dL
D1.4 mg/dL
E2.3 mg/dL
A 62-year-old man comes to the physician because of fatigue and decreased urine output for 2 weeks. He has not been to the physician for many years and takes no medications. Serum studies show a urea nitrogen concentration of 42 mg/dL and a creatinine concentration of 2.3 mg/dL. Urinalysis shows heavy proteinuria. A photomicrograph of a section of a kidney biopsy specimen is shown. Which of the following is the most likely underlying cause of this patient's symptoms?
AAmyloidosis
BDiabetes mellitus
CDyslipidemia
DFibromuscular dysplasia
ESevere hypertension
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