A 17-year-old male presents with altered mental status. He was recently admitted to the hospital due to a tibial fracture suffered while playing soccer. His nurse states that he is difficult to arouse. His temperature is 98.6 deg F (37 deg C), blood pressure is 130/80 mm Hg, pulse is 60/min, and respirations are 6/min. Exam is notable for pinpoint pupils and significant lethargy. Which of the following describes the mechanism of action of the drug likely causing this patient's altered mental status?
ANeuronal hyperpolarization due to sodium influx
BNeuronal depolarization due to sodium efflux
CNeuronal depolarization due to potassium influx
DNeuronal hyperpolarization due to potassium efflux
ENeuronal hyperpolarization due to chloride influx
Two hours after undergoing elective cholecystectomy with general anesthesia, a 41-year-old woman is evaluated for decreased mental status. BMI is 36.6 kg/m2. Respirations are 18/min and blood pressure is 126/73 mm Hg. Physical examination shows the endotracheal tube in normal position. She does not respond to sternal rub and gag reflex is absent. Arterial blood gas analysis on room air shows normal PO2 and PCO2 levels. Which of the following anesthetic properties is the most likely cause of these findings?
ALow blood solubility
BHigh lipid solubility
CLow brain-blood partition coefficient
DHigh minimal alveolar concentration
ELow cytochrome P450 activity
A group of researchers is studying various inhaled substances to determine their anesthetic properties. In particular, they are trying to identify an anesthetic with fast onset and quick recovery for use in emergencies. They determine the following data: Inhalational anesthetic Blood-gas partition coefficient A 0.15 B 0.92 C 5.42 Which of the following statements is accurate with regard to these inhaled anesthetic substances?
AAgent C has the fastest onset of action
BAgent A has the fastest onset of action
CAgent B is the most potent
DAgent B has the fastest onset of action
EAgent A is the most potent
+ 7 more in the PDF
Browse all chapters