Chapter·PathologyCell injury

Hyperplasia and metaplasiaDownloads

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1

A 52-year-old Caucasian male presents to your office complaining of black, tarry stool. Which of the following possible causes of this patient's presentation is LEAST associated with the development of carcinoma?

AAdenomatous polyp

BH. pylori infection

CGastric ulcer

DBarrett's esophagus

EDuodenal ulcer

2

A 34-year-old man with worsening refractory epigastric pain secondary to long-standing gastroesophageal reflux disease presents for endoscopic evaluation. Past medical history is also significant for type 2 diabetes mellitus that was diagnosed 3 years ago, managed medically. Current medications are metformin, metoclopramide, and omeprazole. Which of the following best describes this patient’s most likely endoscopic findings?

AEsophageal smooth muscle atrophy

BMetaplasia of the esophageal mucosa

CA malignant proliferation of squamous cells

DHypertrophy of the esophageal mucosa protruding into the lumen of the lower esophagus

ELongitudinal lacerations of the esophageal mucosa

3

A 35-year-old man comes to the physician for evaluation of a neck mass and hoarseness. He has no history of major medical illness. Physical examination shows a 2.5-cm fixed, irregular thyroid nodule. His serum calcitonin concentration is elevated. The nodule is most likely comprised of cells that are embryologically derived from which of the following structures?

ASecond branchial pouch

BFourth branchial arch

CSurface ectoderm

DThird branchial pouch

ENeural crest cells

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