Chapter·MicrobiologyMicrobial genetics and drug resistance

Bacterial genome structureDownloads

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1

The surgical equipment used during a craniectomy is sterilized using pressurized steam at 121°C for 15 minutes. Reuse of these instruments can cause transmission of which of the following pathogens?

ANon-enveloped viruses

BSporulating bacteria

CPrions

DEnveloped viruses

EYeasts

2

A 61-year-old woman is brought to the emergency department because of fever, chills, and flank pain for 8 hours. Her temperature is 39.1°C (102.4°F). Physical examination shows right costovertebral angle tenderness. Urine dipstick is positive for nitrites. Urinalysis shows gram-negative rods. The patient is admitted to the hospital and treatment with a drug that directly inhibits bacterial DNA replication is begun. This drug inhibits a protein that is normally responsible for which of the following steps of DNA replication?

AExcising RNA fragments in 5' to 3' direction

BCleaving DNA to relieve supercoils

CBinding to single-stranded DNA to prevent reannealing

DUnwinding DNA at replication fork

EJoining of short DNA fragments

3

An investigator is studying the growth of an organism in different media. The organism is inoculated on a petri dish that contains heated sheep blood, vancomycin, nystatin, trimethoprim, and colistin. The resulting growth medium is incubated at 37°C. Numerous small, white colonies are seen after incubation for 48 hours. This organism is most likely to cause which of the following conditions?

APontiac fever

BPseudomembranous colitis

CHemolytic uremic syndrome

DOral thrush

EGonorrhea

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