Chapter·MicrobiologyAtypical

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1

A 29-year-old woman is brought to the emergency department after an episode of syncope. For the past 10 days, she has had dyspnea and palpitations occurring with mild exertion. The patient returned from a hiking trip in Upstate New York 5 weeks ago. Except for an episode of flu with fever and chills a month ago, she has no history of serious illness. Her temperature is 37.3°C (99.1°F), pulse is 45/min, respirations are 21/min, and blood pressure is 148/72 mm Hg. A resting ECG is shown. Two-step serological testing confirms the diagnosis. Which of the following is the most appropriate treatment?

AIntravenous ceftriaxone

BAtropine

COral doxycycline

DBeta blocker

EPermanent pacemaker implantation

2

A 45-year-old woman presents to the emergency department with a headache, fevers with chills, rigors, and generalized joint pain for the past week. She also complains of a progressive rash on her left arm. She says that a few days ago she noticed a small, slightly raised lesion resembling an insect bite mark, which had a burning sensation. The medical and surgical histories are unremarkable. She recalls walking in the woods 2 weeks prior to the onset of symptoms, but does not recall finding a tick on her body. On examination, the temperature is 40.2°C (104.4°F). A circular red rash measuring 10 cm x 5 cm in diameter is noted on the left arm, as shown in the accompanying image. The remainder of her physical examination is unremarkable. The tick causing her disease is also responsible for the transmission of which of the following pathogens?

ARickettsia rickettsii

BBabesia microti

CRickettsia typhi

DEhrlichia

EPlasmodium vivax

3

A 21-year-old man comes to the physician's office due to a 3-week history of fatigue and a rash, along with the recent development of joint pain that has moved from his knee to his elbows. The patient reports going camping last month but denies having been bitten by a tick. His past medical history is significant for asthma treated with an albuterol inhaler. His pulse is 54/min and blood pressure is 110/72. Physical examination reveals multiple circular red rings with central clearings on the right arm and chest. There is a normal range of motion in all joints and 5/5 strength bilaterally in the upper and lower extremities. Without proper treatment, the patient is at highest risk for which of the following complications?

ALiver capsule inflammation

BBone marrow failure

CHeart valve stenosis

DGlomerular damage

ECranial nerve palsy

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