A 53-year old man presents for a well physical examination. He reports his diet is suboptimal, but otherwise reports a healthy lifestyle. He has no past medical history and only takes a multivitamin. He has a blood pressure of 116/74 mm Hg and a pulse of 76/min. On physical examination, he is in no acute distress, has no cardiac murmurs, and his lung sounds are clear to auscultation bilaterally. You order a lipid panel that returns as follows: LDL 203, HDL 37, TG 292. Of the following, which medication should be initiated?
AEzetimibe 10 mg daily
BColesevelam 3.75 grams daily
CAtorvastatin 40 mg daily
DFenofibrate 145 mg daily
ESimvastatin 10 mg daily
A previously healthy 61-year-old man comes to the physician because of a 6-month history of morning headaches. He also has fatigue and trouble concentrating on his daily tasks at work. He sleeps for 8 hours every night; his wife reports that he sometimes stops breathing for a few seconds while sleeping. His pulse is 71/min and blood pressure is 158/96 mm Hg. He is 178 cm (5 ft 10 in) tall and weighs 100 kg (220 lb); BMI is 31.6 kg/m2 . Which of the following is the most likely cause of this patient's hypertension?
AProliferation of adrenal chromaffin cells
BOverproduction of cortisol
CHypophyseal neoplasm
DNocturnal upper airway obstruction
EHypersecretion of aldosterone
A peripheral artery is found to have 50% stenosis (50% reduction in cross-sectional area). Therefore, compared to a normal artery with no stenosis, by what factor has the flow of blood been decreased?
A8
B2
C32
D16
E4
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