A mother presents to the family physician with her 16-year-old son. She explains, "There's something wrong with him doc. His grades are getting worse, he's cutting class, he's gaining weight, and his eyes are often bloodshot." Upon interviewing the patient apart from his mother, he seems withdrawn and angry at times when probed about his social history. The patient denies abuse and sexual history. What initial test should be sent to rule out the most likely culprit of this patient's behavior?
AComplete blood count
BSexually transmitted infection (STI) testing
CBlood culture
DUrine toxicology screen
ESlit lamp examination
A home drug screening test kit is currently being developed. The cut-off level is initially set at 4 mg/uL, which is associated with a sensitivity of 92% and a specificity of 97%. How might the sensitivity and specificity of the test change if the cut-off level is changed to 2 mg/uL?
ASensitivity = 92%, specificity = 97%
BSensitivity = 95%, specificity = 98%
CSensitivity = 100%, specificity = 97%
DSensitivity = 90%, specificity = 99%
ESensitivity = 97%, specificity = 96%
You are developing a new diagnostic test to identify patients with disease X. Of 100 patients tested with the gold standard test, 10% tested positive. Of those that tested positive, the experimental test was positive for 90% of those patients. The specificity of the experimental test is 20%. What is the positive predictive value of this new test?
A10%
B90%
C95%
D11%
E20%
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