You are developing a new diagnostic test to identify patients with disease X. Of 100 patients tested with the gold standard test, 10% tested positive. Of those that tested positive, the experimental test was positive for 90% of those patients. The specificity of the experimental test is 20%. What is the positive predictive value of this new test?
A10%
B90%
C95%
D11%
E20%
A geriatric investigator is evaluating the consistency of Alzheimer dementia diagnoses based on clinical symptoms. Patients with known chart diagnoses of Alzheimer dementia were evaluated by multiple physicians during a fixed time interval. Each evaluator was blinded to the others' assessments. The extent to which the diagnosis by one physician was replicated by another clinician examining the same patient is best described by which of the following terms?
AValidity
BSpecificity
CPredictive value
DSensitivity
EPrecision
You conduct a medical research study to determine the screening efficacy of a novel serum marker for colon cancer. The study is divided into 2 subsets. In the first, there are 500 patients with colon cancer, of which 450 are found positive for the novel serum marker. In the second arm, there are 500 patients who do not have colon cancer, and only 10 are found positive for the novel serum marker. What is the overall sensitivity of this novel test?
A450 / (450 + 10)
B490 / (10 + 490)
C490 / (50 + 490)
D450 / (450 + 50)
E490 / (450 + 490)
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