Chapter·BiostatisticsRCTs

Inclusion and exclusion criteriaDownloads

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Sample Questions

1

A study is funded by the tobacco industry to examine the association between smoking and lung cancer. They design a study with a prospective cohort of 1,000 smokers between the ages of 20-30. The length of the study is five years. After the study period ends, they conclude that there is no relationship between smoking and lung cancer. Which of the following study features is the most likely reason for the failure of the study to note an association between tobacco use and cancer?

ALate-look bias

BLatency period

CConfounding

DEffect modification

EPygmalion effect

2

A pharmaceutical corporation has asked you to assist in the development of a randomized controlled trial (RCT) to evaluate the response of renal cell carcinoma to a novel chemotherapeutic agent. Despite all of the benefits that an RCT has to offer, which of the following would make an RCT unacceptable with regard to study design?

AProper treatment response is very common

BThe treatment is not widespread in use

CThe treatment does not represent the best known option

DThe treatment is expensive

EThe treatment has a known, adverse outcome

3

An investigator is measuring the blood calcium level in a sample of female cross country runners and a control group of sedentary females. If she would like to compare the means of the two groups, which statistical test should she use?

AChi-square test

BLinear regression

Ct-test

DANOVA (Analysis of Variance)

EF-test

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